New mutations in chronic lymphocytic leukemia identified by target enrichment and deep sequencing.

New mutations in chronic lymphocytic leukemia identified by target enrichment and deep sequencing.

Chronic lymphocytic leukemia (CLL) is a heterogeneous disease without a well-defined genetic alteration responsible for the onset of the disease. Several lines of evidence coincide in identifying stimulatory and growth signals delivered by B-cell receptor (BCR), and co-receptors together with NFkB p...

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Main Authors: Elena Doménech, Gonzalo Gómez-López, Daniel Gzlez-Peña, Mar López, Beatriz Herreros, Juliane Menezes, Natalia Gómez-Lozano, Angel Carro, Osvaldo Graña, David G Pisano, Orlando Domínguez, José A García-Marco, Miguel A Piris, Margarita Sánchez-Beato
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/1dbd48f719ae4b53950b5d1f9b7cc0eb
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