SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication

During SARS-CoV-2 replication subgenomic RNAs (sgRNA) are transcribed and subsequently translated into viral proteins. Here, Alexandersen et al. provide evidence that sgRNA is not necessarily an indicator for active viral replication, but can be detected up to 17 days after symptom onset in clinical...

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Autores principales:	Soren Alexandersen, Anthony Chamings, Tarka Raj Bhatta
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1dc4779f10e94dc8b02c7380bc1137b6
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spelling	oai:doaj.org-article:1dc4779f10e94dc8b02c7380bc1137b62021-12-02T14:40:40ZSARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication10.1038/s41467-020-19883-72041-1723https://doaj.org/article/1dc4779f10e94dc8b02c7380bc1137b62020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19883-7https://doaj.org/toc/2041-1723During SARS-CoV-2 replication subgenomic RNAs (sgRNA) are transcribed and subsequently translated into viral proteins. Here, Alexandersen et al. provide evidence that sgRNA is not necessarily an indicator for active viral replication, but can be detected up to 17 days after symptom onset in clinical samples.Soren AlexandersenAnthony ChamingsTarka Raj BhattaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Soren Alexandersen Anthony Chamings Tarka Raj Bhatta SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication
description	During SARS-CoV-2 replication subgenomic RNAs (sgRNA) are transcribed and subsequently translated into viral proteins. Here, Alexandersen et al. provide evidence that sgRNA is not necessarily an indicator for active viral replication, but can be detected up to 17 days after symptom onset in clinical samples.
format	article
author	Soren Alexandersen Anthony Chamings Tarka Raj Bhatta
author_facet	Soren Alexandersen Anthony Chamings Tarka Raj Bhatta
author_sort	Soren Alexandersen
title	SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication
title_short	SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication
title_full	SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication
title_fullStr	SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication
title_full_unstemmed	SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication
title_sort	sars-cov-2 genomic and subgenomic rnas in diagnostic samples are not an indicator of active replication
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/1dc4779f10e94dc8b02c7380bc1137b6
work_keys_str_mv	AT sorenalexandersen sarscov2genomicandsubgenomicrnasindiagnosticsamplesarenotanindicatorofactivereplication AT anthonychamings sarscov2genomicandsubgenomicrnasindiagnosticsamplesarenotanindicatorofactivereplication AT tarkarajbhatta sarscov2genomicandsubgenomicrnasindiagnosticsamplesarenotanindicatorofactivereplication
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SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication

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