Methods for neovagina creation in women with Mayer-Rokitansky-Küster-Hauser syndrome for subsequent uterus transplantation

Mayer-Rokitansky-Küster-Hauser syndrome is a rare female congenital anomaly that presents with an inability to have coital sexual intercourse and absolute uterine factor infertility. Both surgical and nonsurgical approaches have been described for the treatment of vaginal agenesis to allow satisfact...

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Autores principales:	Roman Chmel, Zlatko Pastor, Marta Novackova, Nikoleta Chubanovova
Formato:	article
Lenguaje:	EN
Publicado:	Palacký University Olomouc, Faculty of Medicine and Dentistry 2021
Materias:	absolute uterine factor infertility dilation mayer-rokitansky-küster-hauser syndrome neovagina uterus transplantation vecchietti's method Medicine R
Acceso en línea:	https://doaj.org/article/1dd5ad21f64447a794e0edaa7051df99
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spelling	oai:doaj.org-article:1dd5ad21f64447a794e0edaa7051df992021-11-29T09:17:21ZMethods for neovagina creation in women with Mayer-Rokitansky-Küster-Hauser syndrome for subsequent uterus transplantation1213-81181804-7521https://doaj.org/article/1dd5ad21f64447a794e0edaa7051df992021-11-01T00:00:00Zhttps://biomed.papers.upol.cz/artkey/bio-202104-0002_methods-for-neovagina-creation-in-women-with-mayer-rokitansky-k-ster-hauser-syndrome-for-subsequent-uterus-tran.phphttps://doaj.org/toc/1213-8118https://doaj.org/toc/1804-7521Mayer-Rokitansky-Küster-Hauser syndrome is a rare female congenital anomaly that presents with an inability to have coital sexual intercourse and absolute uterine factor infertility. Both surgical and nonsurgical approaches have been described for the treatment of vaginal agenesis to allow satisfactory coitus. Transplantation of the uterus has the challenge of achieving pregnancy and delivery of her own genetic and biological children in a woman without a natural uterus. Women of reproductive age with a congenital form of absolute uterine factor infertility are considered appropriate recipients of a uterus in the experimental phase of uterus transplantation trials. A neovagina in the normal anatomic position covered by natural non-keratinized mucosa is one of the main assumptions for surgical and reproductive success in transplant recipients. More than 70 uterine transplants have been performed to date, and more than 25 childbirths have been achieved by several research centers in the recipients of a uterus with uterine agenesis. In women with Mayer-Rokitansky-Küster-Hauser syndrome, skin-graft neovagina, Vecchietti's vaginoplasty, and self-dilation using Frank's and Ingram's methods are appropriate techniques to create a neovagina if transplantation of the uterus is intended in the future.Roman ChmelZlatko PastorMarta NovackovaNikoleta ChubanovovaRoman ChmelPalacký University Olomouc, Faculty of Medicine and Dentistryarticleabsolute uterine factor infertilitydilationmayer-rokitansky-küster-hauser syndromeneovaginauterus transplantationvecchietti's methodMedicineRENBiomedical Papers, Vol 165, Iss 4, Pp 360-366 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	absolute uterine factor infertility dilation mayer-rokitansky-küster-hauser syndrome neovagina uterus transplantation vecchietti's method Medicine R
spellingShingle	absolute uterine factor infertility dilation mayer-rokitansky-küster-hauser syndrome neovagina uterus transplantation vecchietti's method Medicine R Roman Chmel Zlatko Pastor Marta Novackova Nikoleta Chubanovova Roman Chmel Methods for neovagina creation in women with Mayer-Rokitansky-Küster-Hauser syndrome for subsequent uterus transplantation
description	Mayer-Rokitansky-Küster-Hauser syndrome is a rare female congenital anomaly that presents with an inability to have coital sexual intercourse and absolute uterine factor infertility. Both surgical and nonsurgical approaches have been described for the treatment of vaginal agenesis to allow satisfactory coitus. Transplantation of the uterus has the challenge of achieving pregnancy and delivery of her own genetic and biological children in a woman without a natural uterus. Women of reproductive age with a congenital form of absolute uterine factor infertility are considered appropriate recipients of a uterus in the experimental phase of uterus transplantation trials. A neovagina in the normal anatomic position covered by natural non-keratinized mucosa is one of the main assumptions for surgical and reproductive success in transplant recipients. More than 70 uterine transplants have been performed to date, and more than 25 childbirths have been achieved by several research centers in the recipients of a uterus with uterine agenesis. In women with Mayer-Rokitansky-Küster-Hauser syndrome, skin-graft neovagina, Vecchietti's vaginoplasty, and self-dilation using Frank's and Ingram's methods are appropriate techniques to create a neovagina if transplantation of the uterus is intended in the future.
format	article
author	Roman Chmel Zlatko Pastor Marta Novackova Nikoleta Chubanovova Roman Chmel
author_facet	Roman Chmel Zlatko Pastor Marta Novackova Nikoleta Chubanovova Roman Chmel
author_sort	Roman Chmel
title	Methods for neovagina creation in women with Mayer-Rokitansky-Küster-Hauser syndrome for subsequent uterus transplantation
title_short	Methods for neovagina creation in women with Mayer-Rokitansky-Küster-Hauser syndrome for subsequent uterus transplantation
title_full	Methods for neovagina creation in women with Mayer-Rokitansky-Küster-Hauser syndrome for subsequent uterus transplantation
title_fullStr	Methods for neovagina creation in women with Mayer-Rokitansky-Küster-Hauser syndrome for subsequent uterus transplantation
title_full_unstemmed	Methods for neovagina creation in women with Mayer-Rokitansky-Küster-Hauser syndrome for subsequent uterus transplantation
title_sort	methods for neovagina creation in women with mayer-rokitansky-küster-hauser syndrome for subsequent uterus transplantation
publisher	Palacký University Olomouc, Faculty of Medicine and Dentistry
publishDate	2021
url	https://doaj.org/article/1dd5ad21f64447a794e0edaa7051df99
work_keys_str_mv	AT romanchmel methodsforneovaginacreationinwomenwithmayerrokitanskykusterhausersyndromeforsubsequentuterustransplantation AT zlatkopastor methodsforneovaginacreationinwomenwithmayerrokitanskykusterhausersyndromeforsubsequentuterustransplantation AT martanovackova methodsforneovaginacreationinwomenwithmayerrokitanskykusterhausersyndromeforsubsequentuterustransplantation AT nikoletachubanovova methodsforneovaginacreationinwomenwithmayerrokitanskykusterhausersyndromeforsubsequentuterustransplantation AT romanchmel methodsforneovaginacreationinwomenwithmayerrokitanskykusterhausersyndromeforsubsequentuterustransplantation
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Methods for neovagina creation in women with Mayer-Rokitansky-Küster-Hauser syndrome for subsequent uterus transplantation

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