Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas
Infant gliomas behave differently to their childhood or adult counterparts. Here, the authors perform a large-scale genetic analysis of these tumours, revealing genetic alterations which may offer therapeutic opportunities.
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Nature Portfolio
2019
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oai:doaj.org-article:1dd77b35b12f4fbfa3be4dbd3feb1c2b2021-12-02T16:58:14ZAlterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas10.1038/s41467-019-12187-52041-1723https://doaj.org/article/1dd77b35b12f4fbfa3be4dbd3feb1c2b2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12187-5https://doaj.org/toc/2041-1723Infant gliomas behave differently to their childhood or adult counterparts. Here, the authors perform a large-scale genetic analysis of these tumours, revealing genetic alterations which may offer therapeutic opportunities.Ana S. Guerreiro StucklinScott RyallKohei FukuokaMichal ZapotockyAlvaro LassalettaChristopher LiTaylor BridgeByungjin KimAnthony ArnoldoPaul E. KowalskiYvonne ZhongMonique JohnsonClaire LiArun K. RamaniRobert SiddawayLiana Figueiredo NobrePasqualino de AntonellisChristopher DunhamSylvia ChengDaniel R. BouéJonathan L. FinlayScott L. CovenInmaculada de PradaMarta Perez-SomarribaClaudia C. FariaMichael A. GrotzerElisabeth RushingDavid SumerauerJosef ZamecnikLenka KrskovaMiguel Garcia ArizaOfelia CruzAndres Morales La MadridPalma SolanoKeita TerashimaYoshiko NakanoKoichi IchimuraMotoo NaganeHiroaki SakamotoMaria Joao Gil-da-CostaRoberto SilvaDonna L. JohnstonJean MichaudBev WilsonFrank K. H. van LandeghemAngelica OviedoP. Daniel McNeelyBruce CrooksIris FriedNataliya ZhukovaJordan R. HansfordAmulya NageswararaoLivia GarziaMary ShagoMichael BrudnoMeredith S. IrwinUte BartelsVijay RamaswamyEric BouffetMichael D. TaylorUri TaboriCynthia HawkinsNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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DOAJ |
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Science Q |
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Science Q Ana S. Guerreiro Stucklin Scott Ryall Kohei Fukuoka Michal Zapotocky Alvaro Lassaletta Christopher Li Taylor Bridge Byungjin Kim Anthony Arnoldo Paul E. Kowalski Yvonne Zhong Monique Johnson Claire Li Arun K. Ramani Robert Siddaway Liana Figueiredo Nobre Pasqualino de Antonellis Christopher Dunham Sylvia Cheng Daniel R. Boué Jonathan L. Finlay Scott L. Coven Inmaculada de Prada Marta Perez-Somarriba Claudia C. Faria Michael A. Grotzer Elisabeth Rushing David Sumerauer Josef Zamecnik Lenka Krskova Miguel Garcia Ariza Ofelia Cruz Andres Morales La Madrid Palma Solano Keita Terashima Yoshiko Nakano Koichi Ichimura Motoo Nagane Hiroaki Sakamoto Maria Joao Gil-da-Costa Roberto Silva Donna L. Johnston Jean Michaud Bev Wilson Frank K. H. van Landeghem Angelica Oviedo P. Daniel McNeely Bruce Crooks Iris Fried Nataliya Zhukova Jordan R. Hansford Amulya Nageswararao Livia Garzia Mary Shago Michael Brudno Meredith S. Irwin Ute Bartels Vijay Ramaswamy Eric Bouffet Michael D. Taylor Uri Tabori Cynthia Hawkins Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas |
| description |
Infant gliomas behave differently to their childhood or adult counterparts. Here, the authors perform a large-scale genetic analysis of these tumours, revealing genetic alterations which may offer therapeutic opportunities. |
| format |
article |
| author |
Ana S. Guerreiro Stucklin Scott Ryall Kohei Fukuoka Michal Zapotocky Alvaro Lassaletta Christopher Li Taylor Bridge Byungjin Kim Anthony Arnoldo Paul E. Kowalski Yvonne Zhong Monique Johnson Claire Li Arun K. Ramani Robert Siddaway Liana Figueiredo Nobre Pasqualino de Antonellis Christopher Dunham Sylvia Cheng Daniel R. Boué Jonathan L. Finlay Scott L. Coven Inmaculada de Prada Marta Perez-Somarriba Claudia C. Faria Michael A. Grotzer Elisabeth Rushing David Sumerauer Josef Zamecnik Lenka Krskova Miguel Garcia Ariza Ofelia Cruz Andres Morales La Madrid Palma Solano Keita Terashima Yoshiko Nakano Koichi Ichimura Motoo Nagane Hiroaki Sakamoto Maria Joao Gil-da-Costa Roberto Silva Donna L. Johnston Jean Michaud Bev Wilson Frank K. H. van Landeghem Angelica Oviedo P. Daniel McNeely Bruce Crooks Iris Fried Nataliya Zhukova Jordan R. Hansford Amulya Nageswararao Livia Garzia Mary Shago Michael Brudno Meredith S. Irwin Ute Bartels Vijay Ramaswamy Eric Bouffet Michael D. Taylor Uri Tabori Cynthia Hawkins |
| author_facet |
Ana S. Guerreiro Stucklin Scott Ryall Kohei Fukuoka Michal Zapotocky Alvaro Lassaletta Christopher Li Taylor Bridge Byungjin Kim Anthony Arnoldo Paul E. Kowalski Yvonne Zhong Monique Johnson Claire Li Arun K. Ramani Robert Siddaway Liana Figueiredo Nobre Pasqualino de Antonellis Christopher Dunham Sylvia Cheng Daniel R. Boué Jonathan L. Finlay Scott L. Coven Inmaculada de Prada Marta Perez-Somarriba Claudia C. Faria Michael A. Grotzer Elisabeth Rushing David Sumerauer Josef Zamecnik Lenka Krskova Miguel Garcia Ariza Ofelia Cruz Andres Morales La Madrid Palma Solano Keita Terashima Yoshiko Nakano Koichi Ichimura Motoo Nagane Hiroaki Sakamoto Maria Joao Gil-da-Costa Roberto Silva Donna L. Johnston Jean Michaud Bev Wilson Frank K. H. van Landeghem Angelica Oviedo P. Daniel McNeely Bruce Crooks Iris Fried Nataliya Zhukova Jordan R. Hansford Amulya Nageswararao Livia Garzia Mary Shago Michael Brudno Meredith S. Irwin Ute Bartels Vijay Ramaswamy Eric Bouffet Michael D. Taylor Uri Tabori Cynthia Hawkins |
| author_sort |
Ana S. Guerreiro Stucklin |
| title |
Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas |
| title_short |
Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas |
| title_full |
Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas |
| title_fullStr |
Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas |
| title_full_unstemmed |
Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas |
| title_sort |
alterations in alk/ros1/ntrk/met drive a group of infantile hemispheric gliomas |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/1dd77b35b12f4fbfa3be4dbd3feb1c2b |
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