Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection

Kiyoshi Suzuma, Eiko Tsuiki, Makiko Matsumoto, Azusa Fujikawa, Takashi KitaokaDepartment of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, JapanAbstract: The F10 is a new commercially available scanning laser confocal ophthalmoscope (SLO) th...

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Autores principales: Fujikawa A, Matsumoto M, Tsuiki E, Suzuma K, Kitaoka T
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Publicado: Dove Medical Press 2011
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spelling oai:doaj.org-article:1de25ffdf70f42afaf1b49dc916300142021-12-02T00:17:02ZRetro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection1177-54671177-5483https://doaj.org/article/1de25ffdf70f42afaf1b49dc916300142011-06-01T00:00:00Zhttp://www.dovepress.com/retro-mode-imaging-of-fibrovascular-membrane-in-proliferative-diabetic-a7778https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Kiyoshi Suzuma, Eiko Tsuiki, Makiko Matsumoto, Azusa Fujikawa, Takashi KitaokaDepartment of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, JapanAbstract: The F10 is a new commercially available scanning laser confocal ophthalmoscope (SLO) that can perform multiple functions. We determined the usefulness of noninvasive evaluation of proliferative diabetic retinopathy (PDR) pathologies before and after intravitreal injection of bevacizumab (IVB) using the new indirect viewing system of the retro-mode function of the F10 SLO, and compared the images histologically with surgically excised fibrovascular membrane from two cases. In PDR, neovascular vessels in fibrovascular membrane were clearly seen with the retro-mode, even after IVB and without blood flow. The F10 SLO may be useful in evaluating neovascular vessels in fibrovascular membrane in PDR and for determining the precise retinal changes in diabetic retinopathy.Keywords: bevacizumab, imaging, proliferative diabetic retinopathy, retro-mode, scanning laser ophthalmoscopeFujikawa AMatsumoto MTsuiki ESuzuma KKitaoka TDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 897-900 (2011)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Fujikawa A
Matsumoto M
Tsuiki E
Suzuma K
Kitaoka T
Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection
description Kiyoshi Suzuma, Eiko Tsuiki, Makiko Matsumoto, Azusa Fujikawa, Takashi KitaokaDepartment of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, JapanAbstract: The F10 is a new commercially available scanning laser confocal ophthalmoscope (SLO) that can perform multiple functions. We determined the usefulness of noninvasive evaluation of proliferative diabetic retinopathy (PDR) pathologies before and after intravitreal injection of bevacizumab (IVB) using the new indirect viewing system of the retro-mode function of the F10 SLO, and compared the images histologically with surgically excised fibrovascular membrane from two cases. In PDR, neovascular vessels in fibrovascular membrane were clearly seen with the retro-mode, even after IVB and without blood flow. The F10 SLO may be useful in evaluating neovascular vessels in fibrovascular membrane in PDR and for determining the precise retinal changes in diabetic retinopathy.Keywords: bevacizumab, imaging, proliferative diabetic retinopathy, retro-mode, scanning laser ophthalmoscope
format article
author Fujikawa A
Matsumoto M
Tsuiki E
Suzuma K
Kitaoka T
author_facet Fujikawa A
Matsumoto M
Tsuiki E
Suzuma K
Kitaoka T
author_sort Fujikawa A
title Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection
title_short Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection
title_full Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection
title_fullStr Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection
title_full_unstemmed Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection
title_sort retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/1de25ffdf70f42afaf1b49dc91630014
work_keys_str_mv AT fujikawaa retromodeimagingoffibrovascularmembraneinproliferativediabeticretinopathyafterintravitrealbevacizumabinjection
AT matsumotom retromodeimagingoffibrovascularmembraneinproliferativediabeticretinopathyafterintravitrealbevacizumabinjection
AT tsuikie retromodeimagingoffibrovascularmembraneinproliferativediabeticretinopathyafterintravitrealbevacizumabinjection
AT suzumak retromodeimagingoffibrovascularmembraneinproliferativediabeticretinopathyafterintravitrealbevacizumabinjection
AT kitaokat retromodeimagingoffibrovascularmembraneinproliferativediabeticretinopathyafterintravitrealbevacizumabinjection
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