Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast
Termination of RNA polymerase II (RNAPII) transcription is an essential step of gene expression. Here the authors provide evidence that in fission yeast termination of ncRNA genes occurs by a cleavage-dependent mechanism involving recruitment of mRNA 3′ end processing factors and requires the conser...
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Nature Portfolio
2018
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oai:doaj.org-article:1de494ea30714a22bec8e626430ecc542021-12-02T14:41:17ZCommon mechanism of transcription termination at coding and noncoding RNA genes in fission yeast10.1038/s41467-018-06546-x2041-1723https://doaj.org/article/1de494ea30714a22bec8e626430ecc542018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06546-xhttps://doaj.org/toc/2041-1723Termination of RNA polymerase II (RNAPII) transcription is an essential step of gene expression. Here the authors provide evidence that in fission yeast termination of ncRNA genes occurs by a cleavage-dependent mechanism involving recruitment of mRNA 3′ end processing factors and requires the conserved Ysh1/CPSF-73 and Dhp1/XRN2 nucleases.Marc LarochelleMarc-Antoine RobertJean-Nicolas HébertXiaochuan LiuDominick MatteauSébastien RodrigueBin TianPierre-Étienne JacquesFrançois BachandNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
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DOAJ |
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EN |
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Science Q |
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Science Q Marc Larochelle Marc-Antoine Robert Jean-Nicolas Hébert Xiaochuan Liu Dominick Matteau Sébastien Rodrigue Bin Tian Pierre-Étienne Jacques François Bachand Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast |
description |
Termination of RNA polymerase II (RNAPII) transcription is an essential step of gene expression. Here the authors provide evidence that in fission yeast termination of ncRNA genes occurs by a cleavage-dependent mechanism involving recruitment of mRNA 3′ end processing factors and requires the conserved Ysh1/CPSF-73 and Dhp1/XRN2 nucleases. |
format |
article |
author |
Marc Larochelle Marc-Antoine Robert Jean-Nicolas Hébert Xiaochuan Liu Dominick Matteau Sébastien Rodrigue Bin Tian Pierre-Étienne Jacques François Bachand |
author_facet |
Marc Larochelle Marc-Antoine Robert Jean-Nicolas Hébert Xiaochuan Liu Dominick Matteau Sébastien Rodrigue Bin Tian Pierre-Étienne Jacques François Bachand |
author_sort |
Marc Larochelle |
title |
Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast |
title_short |
Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast |
title_full |
Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast |
title_fullStr |
Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast |
title_full_unstemmed |
Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast |
title_sort |
common mechanism of transcription termination at coding and noncoding rna genes in fission yeast |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/1de494ea30714a22bec8e626430ecc54 |
work_keys_str_mv |
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_version_ |
1718389916299165696 |