Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast

Termination of RNA polymerase II (RNAPII) transcription is an essential step of gene expression. Here the authors provide evidence that in fission yeast termination of ncRNA genes occurs by a cleavage-dependent mechanism involving recruitment of mRNA 3′ end processing factors and requires the conser...

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Autores principales: Marc Larochelle, Marc-Antoine Robert, Jean-Nicolas Hébert, Xiaochuan Liu, Dominick Matteau, Sébastien Rodrigue, Bin Tian, Pierre-Étienne Jacques, François Bachand
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1de494ea30714a22bec8e626430ecc54
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spelling oai:doaj.org-article:1de494ea30714a22bec8e626430ecc542021-12-02T14:41:17ZCommon mechanism of transcription termination at coding and noncoding RNA genes in fission yeast10.1038/s41467-018-06546-x2041-1723https://doaj.org/article/1de494ea30714a22bec8e626430ecc542018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06546-xhttps://doaj.org/toc/2041-1723Termination of RNA polymerase II (RNAPII) transcription is an essential step of gene expression. Here the authors provide evidence that in fission yeast termination of ncRNA genes occurs by a cleavage-dependent mechanism involving recruitment of mRNA 3′ end processing factors and requires the conserved Ysh1/CPSF-73 and Dhp1/XRN2 nucleases.Marc LarochelleMarc-Antoine RobertJean-Nicolas HébertXiaochuan LiuDominick MatteauSébastien RodrigueBin TianPierre-Étienne JacquesFrançois BachandNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Marc Larochelle
Marc-Antoine Robert
Jean-Nicolas Hébert
Xiaochuan Liu
Dominick Matteau
Sébastien Rodrigue
Bin Tian
Pierre-Étienne Jacques
François Bachand
Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast
description Termination of RNA polymerase II (RNAPII) transcription is an essential step of gene expression. Here the authors provide evidence that in fission yeast termination of ncRNA genes occurs by a cleavage-dependent mechanism involving recruitment of mRNA 3′ end processing factors and requires the conserved Ysh1/CPSF-73 and Dhp1/XRN2 nucleases.
format article
author Marc Larochelle
Marc-Antoine Robert
Jean-Nicolas Hébert
Xiaochuan Liu
Dominick Matteau
Sébastien Rodrigue
Bin Tian
Pierre-Étienne Jacques
François Bachand
author_facet Marc Larochelle
Marc-Antoine Robert
Jean-Nicolas Hébert
Xiaochuan Liu
Dominick Matteau
Sébastien Rodrigue
Bin Tian
Pierre-Étienne Jacques
François Bachand
author_sort Marc Larochelle
title Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast
title_short Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast
title_full Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast
title_fullStr Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast
title_full_unstemmed Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast
title_sort common mechanism of transcription termination at coding and noncoding rna genes in fission yeast
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/1de494ea30714a22bec8e626430ecc54
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