Diagnostic Value of Imaging Combined With Tumor Markers in Early Detection of Lung Cancer

Objective: The objective of this research is to explore the diagnostic value of imaging plus tumor markers in the early detection of lung cancer.Methods: Sixty patients with lung cancer treated in our hospital from January 2018 to January 2019 were selected as group A. They were matched with 60 pati...

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Autores principales:	Su-Ju Wei, Li-Ping Wang, Jun-Yan Wang, Jing-Xu Ma, Feng-Bin Chuan, Yu-Dong Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	lung cancer imaging tumor markers diagnostic value CEA Surgery RD1-811
Acceso en línea:	https://doaj.org/article/1ded317202f549e0856bfda19fbea1c7
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spelling	oai:doaj.org-article:1ded317202f549e0856bfda19fbea1c72021-12-01T07:11:01ZDiagnostic Value of Imaging Combined With Tumor Markers in Early Detection of Lung Cancer2296-875X10.3389/fsurg.2021.694210https://doaj.org/article/1ded317202f549e0856bfda19fbea1c72021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fsurg.2021.694210/fullhttps://doaj.org/toc/2296-875XObjective: The objective of this research is to explore the diagnostic value of imaging plus tumor markers in the early detection of lung cancer.Methods: Sixty patients with lung cancer treated in our hospital from January 2018 to January 2019 were selected as group A. They were matched with 60 patients with benign lung disease as group B and 60 healthy subjects examined in our hospital as group C. The carcino-embryonic antigen (CEA), CYFRA21-1, and neuron-specific enolase (NSE) were assessed, and the diagnostic value of tumor markers plus imaging in lung cancer diagnosis was explored.Results: The CEA, CYFRA21-1, and NSE in group A were evidently superior to those in groups B and C, and those in group B were superior to those in group C (all P < 0.001). CEA had the highest sensitivity (56.7%), and NSE had the highest specificity (93.3%). The tumor markers plus imaging had the highest sensitivity for different types of lung cancer, and the sensitivity to early lung cancer (90%) was superior to other diagnostic methods (P < 0.05).Conclusion: The tumor markers plus imaging is of great significance in early lung cancer diagnosis and provides a reference for judging the pathological classification.Su-Ju WeiLi-Ping WangJun-Yan WangJing-Xu MaFeng-Bin ChuanYu-Dong ZhangFrontiers Media S.A.articlelung cancerimagingtumor markersdiagnostic valueCEASurgeryRD1-811ENFrontiers in Surgery, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	lung cancer imaging tumor markers diagnostic value CEA Surgery RD1-811
spellingShingle	lung cancer imaging tumor markers diagnostic value CEA Surgery RD1-811 Su-Ju Wei Li-Ping Wang Jun-Yan Wang Jing-Xu Ma Feng-Bin Chuan Yu-Dong Zhang Diagnostic Value of Imaging Combined With Tumor Markers in Early Detection of Lung Cancer
description	Objective: The objective of this research is to explore the diagnostic value of imaging plus tumor markers in the early detection of lung cancer.Methods: Sixty patients with lung cancer treated in our hospital from January 2018 to January 2019 were selected as group A. They were matched with 60 patients with benign lung disease as group B and 60 healthy subjects examined in our hospital as group C. The carcino-embryonic antigen (CEA), CYFRA21-1, and neuron-specific enolase (NSE) were assessed, and the diagnostic value of tumor markers plus imaging in lung cancer diagnosis was explored.Results: The CEA, CYFRA21-1, and NSE in group A were evidently superior to those in groups B and C, and those in group B were superior to those in group C (all P < 0.001). CEA had the highest sensitivity (56.7%), and NSE had the highest specificity (93.3%). The tumor markers plus imaging had the highest sensitivity for different types of lung cancer, and the sensitivity to early lung cancer (90%) was superior to other diagnostic methods (P < 0.05).Conclusion: The tumor markers plus imaging is of great significance in early lung cancer diagnosis and provides a reference for judging the pathological classification.
format	article
author	Su-Ju Wei Li-Ping Wang Jun-Yan Wang Jing-Xu Ma Feng-Bin Chuan Yu-Dong Zhang
author_facet	Su-Ju Wei Li-Ping Wang Jun-Yan Wang Jing-Xu Ma Feng-Bin Chuan Yu-Dong Zhang
author_sort	Su-Ju Wei
title	Diagnostic Value of Imaging Combined With Tumor Markers in Early Detection of Lung Cancer
title_short	Diagnostic Value of Imaging Combined With Tumor Markers in Early Detection of Lung Cancer
title_full	Diagnostic Value of Imaging Combined With Tumor Markers in Early Detection of Lung Cancer
title_fullStr	Diagnostic Value of Imaging Combined With Tumor Markers in Early Detection of Lung Cancer
title_full_unstemmed	Diagnostic Value of Imaging Combined With Tumor Markers in Early Detection of Lung Cancer
title_sort	diagnostic value of imaging combined with tumor markers in early detection of lung cancer
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/1ded317202f549e0856bfda19fbea1c7
work_keys_str_mv	AT sujuwei diagnosticvalueofimagingcombinedwithtumormarkersinearlydetectionoflungcancer AT lipingwang diagnosticvalueofimagingcombinedwithtumormarkersinearlydetectionoflungcancer AT junyanwang diagnosticvalueofimagingcombinedwithtumormarkersinearlydetectionoflungcancer AT jingxuma diagnosticvalueofimagingcombinedwithtumormarkersinearlydetectionoflungcancer AT fengbinchuan diagnosticvalueofimagingcombinedwithtumormarkersinearlydetectionoflungcancer AT yudongzhang diagnosticvalueofimagingcombinedwithtumormarkersinearlydetectionoflungcancer
_version_	1718405399939383296

Diagnostic Value of Imaging Combined With Tumor Markers in Early Detection of Lung Cancer

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