Frequent miRNA-convergent fusion gene events in breast cancer

Fusion gene research traditionally focuses on fusions that result in hybrid proteins or promoter switching events. Here, the authors demonstrate enrichment of fusions in miRNA host genes in breast cancer, highlighting that disparate fusions could have convergent impact on miRNA.

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Autores principales:	Helena Persson, Rolf Søkilde, Jari Häkkinen, Anna Chiara Pirona, Johan Vallon-Christersson, Anders Kvist, Fredrik Mertens, Åke Borg, Felix Mitelman, Mattias Höglund, Carlos Rovira
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1df00dd412b84dc780810f851b6a2ebb
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spelling	oai:doaj.org-article:1df00dd412b84dc780810f851b6a2ebb2021-12-02T14:42:26ZFrequent miRNA-convergent fusion gene events in breast cancer10.1038/s41467-017-01176-12041-1723https://doaj.org/article/1df00dd412b84dc780810f851b6a2ebb2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01176-1https://doaj.org/toc/2041-1723Fusion gene research traditionally focuses on fusions that result in hybrid proteins or promoter switching events. Here, the authors demonstrate enrichment of fusions in miRNA host genes in breast cancer, highlighting that disparate fusions could have convergent impact on miRNA.Helena PerssonRolf SøkildeJari HäkkinenAnna Chiara PironaJohan Vallon-ChristerssonAnders KvistFredrik MertensÅke BorgFelix MitelmanMattias HöglundCarlos RoviraNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Helena Persson Rolf Søkilde Jari Häkkinen Anna Chiara Pirona Johan Vallon-Christersson Anders Kvist Fredrik Mertens Åke Borg Felix Mitelman Mattias Höglund Carlos Rovira Frequent miRNA-convergent fusion gene events in breast cancer
description	Fusion gene research traditionally focuses on fusions that result in hybrid proteins or promoter switching events. Here, the authors demonstrate enrichment of fusions in miRNA host genes in breast cancer, highlighting that disparate fusions could have convergent impact on miRNA.
format	article
author	Helena Persson Rolf Søkilde Jari Häkkinen Anna Chiara Pirona Johan Vallon-Christersson Anders Kvist Fredrik Mertens Åke Borg Felix Mitelman Mattias Höglund Carlos Rovira
author_facet	Helena Persson Rolf Søkilde Jari Häkkinen Anna Chiara Pirona Johan Vallon-Christersson Anders Kvist Fredrik Mertens Åke Borg Felix Mitelman Mattias Höglund Carlos Rovira
author_sort	Helena Persson
title	Frequent miRNA-convergent fusion gene events in breast cancer
title_short	Frequent miRNA-convergent fusion gene events in breast cancer
title_full	Frequent miRNA-convergent fusion gene events in breast cancer
title_fullStr	Frequent miRNA-convergent fusion gene events in breast cancer
title_full_unstemmed	Frequent miRNA-convergent fusion gene events in breast cancer
title_sort	frequent mirna-convergent fusion gene events in breast cancer
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1df00dd412b84dc780810f851b6a2ebb
work_keys_str_mv	AT helenapersson frequentmirnaconvergentfusiongeneeventsinbreastcancer AT rolfsøkilde frequentmirnaconvergentfusiongeneeventsinbreastcancer AT jarihakkinen frequentmirnaconvergentfusiongeneeventsinbreastcancer AT annachiarapirona frequentmirnaconvergentfusiongeneeventsinbreastcancer AT johanvallonchristersson frequentmirnaconvergentfusiongeneeventsinbreastcancer AT anderskvist frequentmirnaconvergentfusiongeneeventsinbreastcancer AT fredrikmertens frequentmirnaconvergentfusiongeneeventsinbreastcancer AT akeborg frequentmirnaconvergentfusiongeneeventsinbreastcancer AT felixmitelman frequentmirnaconvergentfusiongeneeventsinbreastcancer AT mattiashoglund frequentmirnaconvergentfusiongeneeventsinbreastcancer AT carlosrovira frequentmirnaconvergentfusiongeneeventsinbreastcancer
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Frequent miRNA-convergent fusion gene events in breast cancer

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