Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes

Intercalating molecules can significantly change the conformation of DNA. Here, the authors fabricated resonators fully composed of DNA forming bundles between microfabricated pillars to study the vibration property of the DNA bundles with/without intercalant molecules.

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Autores principales:	Stefano Stassi, Monica Marini, Marco Allione, Sergei Lopatin, Domenico Marson, Erik Laurini, Sabrina Pricl, Candido Fabrizio Pirri, Carlo Ricciardi, Enzo Di Fabrizio
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1df5a0fd518d4a9b9c962d7616f37f53
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spelling	oai:doaj.org-article:1df5a0fd518d4a9b9c962d7616f37f532021-12-02T17:31:52ZNanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes10.1038/s41467-019-09612-02041-1723https://doaj.org/article/1df5a0fd518d4a9b9c962d7616f37f532019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09612-0https://doaj.org/toc/2041-1723Intercalating molecules can significantly change the conformation of DNA. Here, the authors fabricated resonators fully composed of DNA forming bundles between microfabricated pillars to study the vibration property of the DNA bundles with/without intercalant molecules.Stefano StassiMonica MariniMarco AllioneSergei LopatinDomenico MarsonErik LauriniSabrina PriclCandido Fabrizio PirriCarlo RicciardiEnzo Di FabrizioNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stefano Stassi Monica Marini Marco Allione Sergei Lopatin Domenico Marson Erik Laurini Sabrina Pricl Candido Fabrizio Pirri Carlo Ricciardi Enzo Di Fabrizio Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes
description	Intercalating molecules can significantly change the conformation of DNA. Here, the authors fabricated resonators fully composed of DNA forming bundles between microfabricated pillars to study the vibration property of the DNA bundles with/without intercalant molecules.
format	article
author	Stefano Stassi Monica Marini Marco Allione Sergei Lopatin Domenico Marson Erik Laurini Sabrina Pricl Candido Fabrizio Pirri Carlo Ricciardi Enzo Di Fabrizio
author_facet	Stefano Stassi Monica Marini Marco Allione Sergei Lopatin Domenico Marson Erik Laurini Sabrina Pricl Candido Fabrizio Pirri Carlo Ricciardi Enzo Di Fabrizio
author_sort	Stefano Stassi
title	Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes
title_short	Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes
title_full	Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes
title_fullStr	Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes
title_full_unstemmed	Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes
title_sort	nanomechanical dna resonators for sensing and structural analysis of dna-ligand complexes
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1df5a0fd518d4a9b9c962d7616f37f53
work_keys_str_mv	AT stefanostassi nanomechanicaldnaresonatorsforsensingandstructuralanalysisofdnaligandcomplexes AT monicamarini nanomechanicaldnaresonatorsforsensingandstructuralanalysisofdnaligandcomplexes AT marcoallione nanomechanicaldnaresonatorsforsensingandstructuralanalysisofdnaligandcomplexes AT sergeilopatin nanomechanicaldnaresonatorsforsensingandstructuralanalysisofdnaligandcomplexes AT domenicomarson nanomechanicaldnaresonatorsforsensingandstructuralanalysisofdnaligandcomplexes AT eriklaurini nanomechanicaldnaresonatorsforsensingandstructuralanalysisofdnaligandcomplexes AT sabrinapricl nanomechanicaldnaresonatorsforsensingandstructuralanalysisofdnaligandcomplexes AT candidofabriziopirri nanomechanicaldnaresonatorsforsensingandstructuralanalysisofdnaligandcomplexes AT carloricciardi nanomechanicaldnaresonatorsforsensingandstructuralanalysisofdnaligandcomplexes AT enzodifabrizio nanomechanicaldnaresonatorsforsensingandstructuralanalysisofdnaligandcomplexes
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Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes

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