Efficacy of Co-trimoxazol and Rifampine in treatment of childhood Brucellosis

Objective: Brucellosis is a common infectious disease in our country and it is frequently seen in children. Since different therapeutic methods for childhood Brucellosis are suggested, this study was performed to evaluate the efficacy of Co-trimoxazol and Rifampine in the treatment of children with...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: MR Hassanjani Roshan, Y ZahedPasha
Formato: article
Lenguaje:EN
FA
Publicado: Babol University of Medical Sciences 2000
Materias:
R
Acceso en línea:https://doaj.org/article/1df62c04479f4b059965f521b20557ed
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:1df62c04479f4b059965f521b20557ed
record_format dspace
spelling oai:doaj.org-article:1df62c04479f4b059965f521b20557ed2021-11-10T09:22:21ZEfficacy of Co-trimoxazol and Rifampine in treatment of childhood Brucellosis1561-41072251-7170https://doaj.org/article/1df62c04479f4b059965f521b20557ed2000-10-01T00:00:00Zhttp://jbums.org/article-1-2890-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Objective: Brucellosis is a common infectious disease in our country and it is frequently seen in children. Since different therapeutic methods for childhood Brucellosis are suggested, this study was performed to evaluate the efficacy of Co-trimoxazol and Rifampine in the treatment of children with Brucellosis. Methods: This study was conducted on 96 cases of childhood Brucellosis without any control group in Babol during 1995 to 1998. After diagnosis of Brucellosis all patients were treated by Co-trimoxazol and Rifampine for six weeks, and then all patients were followed for 12 months. Findings: From a total of 96 cases, 53 (55%) were male and 43 (45%) were female. Mean age was 10.3±3.4 years. The mean interval between presentation of the disease and the final diagnosis was 27±17 days. 82 cases completed the treatment and followed up for 12 months, and 2 cases (2.4%) had relapses. Conclusion: Combination therapy with Co-trimoxazol and Rifampine for six weeks is a good regimen with a low relapse rate, however further controlled trials must confirm these results.MR Hassanjani RoshanY ZahedPashaBabol University of Medical Sciencesarticlebrucellosischildrentreatmentrelapseco-trimoxazolrifampineMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 2, Iss 4, Pp 17-20 (2000)
institution DOAJ
collection DOAJ
language EN
FA
topic brucellosis
children
treatment
relapse
co-trimoxazol
rifampine
Medicine
R
Medicine (General)
R5-920
spellingShingle brucellosis
children
treatment
relapse
co-trimoxazol
rifampine
Medicine
R
Medicine (General)
R5-920
MR Hassanjani Roshan
Y ZahedPasha
Efficacy of Co-trimoxazol and Rifampine in treatment of childhood Brucellosis
description Objective: Brucellosis is a common infectious disease in our country and it is frequently seen in children. Since different therapeutic methods for childhood Brucellosis are suggested, this study was performed to evaluate the efficacy of Co-trimoxazol and Rifampine in the treatment of children with Brucellosis. Methods: This study was conducted on 96 cases of childhood Brucellosis without any control group in Babol during 1995 to 1998. After diagnosis of Brucellosis all patients were treated by Co-trimoxazol and Rifampine for six weeks, and then all patients were followed for 12 months. Findings: From a total of 96 cases, 53 (55%) were male and 43 (45%) were female. Mean age was 10.3±3.4 years. The mean interval between presentation of the disease and the final diagnosis was 27±17 days. 82 cases completed the treatment and followed up for 12 months, and 2 cases (2.4%) had relapses. Conclusion: Combination therapy with Co-trimoxazol and Rifampine for six weeks is a good regimen with a low relapse rate, however further controlled trials must confirm these results.
format article
author MR Hassanjani Roshan
Y ZahedPasha
author_facet MR Hassanjani Roshan
Y ZahedPasha
author_sort MR Hassanjani Roshan
title Efficacy of Co-trimoxazol and Rifampine in treatment of childhood Brucellosis
title_short Efficacy of Co-trimoxazol and Rifampine in treatment of childhood Brucellosis
title_full Efficacy of Co-trimoxazol and Rifampine in treatment of childhood Brucellosis
title_fullStr Efficacy of Co-trimoxazol and Rifampine in treatment of childhood Brucellosis
title_full_unstemmed Efficacy of Co-trimoxazol and Rifampine in treatment of childhood Brucellosis
title_sort efficacy of co-trimoxazol and rifampine in treatment of childhood brucellosis
publisher Babol University of Medical Sciences
publishDate 2000
url https://doaj.org/article/1df62c04479f4b059965f521b20557ed
work_keys_str_mv AT mrhassanjaniroshan efficacyofcotrimoxazolandrifampineintreatmentofchildhoodbrucellosis
AT yzahedpasha efficacyofcotrimoxazolandrifampineintreatmentofchildhoodbrucellosis
_version_ 1718440081049518080