A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding

Secreted cytokine decoy receptors encoded by viruses can act as potent immune evasion proteins modulating antiviral immunity. Here Hernaez et al. show that cell surface binding is required for efficient evasion of the host response by a secreted virus encoded type I IFN decoy receptor of vaccinia an...

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Autores principales:	Bruno Hernáez, Juan Manuel Alonso-Lobo, Imma Montanuy, Cornelius Fischer, Sascha Sauer, Luis Sigal, Noemí Sevilla, Antonio Alcamí
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1dfee90d8c3a4e8582932ce956159076
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spelling	oai:doaj.org-article:1dfee90d8c3a4e8582932ce9561590762021-12-02T16:50:04ZA virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding10.1038/s41467-018-07772-z2041-1723https://doaj.org/article/1dfee90d8c3a4e8582932ce9561590762018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07772-zhttps://doaj.org/toc/2041-1723Secreted cytokine decoy receptors encoded by viruses can act as potent immune evasion proteins modulating antiviral immunity. Here Hernaez et al. show that cell surface binding is required for efficient evasion of the host response by a secreted virus encoded type I IFN decoy receptor of vaccinia and ectromelia virus using an in vivo model of infection.Bruno HernáezJuan Manuel Alonso-LoboImma MontanuyCornelius FischerSascha SauerLuis SigalNoemí SevillaAntonio AlcamíNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bruno Hernáez Juan Manuel Alonso-Lobo Imma Montanuy Cornelius Fischer Sascha Sauer Luis Sigal Noemí Sevilla Antonio Alcamí A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding
description	Secreted cytokine decoy receptors encoded by viruses can act as potent immune evasion proteins modulating antiviral immunity. Here Hernaez et al. show that cell surface binding is required for efficient evasion of the host response by a secreted virus encoded type I IFN decoy receptor of vaccinia and ectromelia virus using an in vivo model of infection.
format	article
author	Bruno Hernáez Juan Manuel Alonso-Lobo Imma Montanuy Cornelius Fischer Sascha Sauer Luis Sigal Noemí Sevilla Antonio Alcamí
author_facet	Bruno Hernáez Juan Manuel Alonso-Lobo Imma Montanuy Cornelius Fischer Sascha Sauer Luis Sigal Noemí Sevilla Antonio Alcamí
author_sort	Bruno Hernáez
title	A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding
title_short	A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding
title_full	A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding
title_fullStr	A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding
title_full_unstemmed	A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding
title_sort	virus-encoded type i interferon decoy receptor enables evasion of host immunity through cell-surface binding
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/1dfee90d8c3a4e8582932ce956159076
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A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding

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