Hematopoietic Id Deletion Triggers Endomyocardial Fibrotic and Vascular Defects in the Adult Heart

Abstract Inhibitor of DNA binding (Id) proteins play important roles in regulating cardiac development via paracrine signaling. Id1/Id3 knockout mice die at mid-gestation with multiple cardiac defects. Single Id knockout studies have not reported cardiomyopathies. To bypass embryonic lethality we us...

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Autores principales: Corey Chang, Qingshi Zhao, J. Patrick Gonzalez, Jung H. Kim, Kamal Alzahrani, Dominic Del Re, Diego Fraidenraich
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/1dfeec54022449938a53188db4229009
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