A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in maintaining genome stability.

A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in maintaining genome stability.

Mutations are a major driving force of evolution and genetic disease. In eukaryotes, mutations are produced in the chromatin environment, but the impact of chromatin on mutagenesis is poorly understood. Previous studies have determined that in yeast Saccharomyces cerevisiae, Rtt109-dependent acetyla...

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Autores principales: Lyudmila Y Kadyrova, Tony M Mertz, Yu Zhang, Matthew R Northam, Ziwei Sheng, Kirill S Lobachev, Polina V Shcherbakova, Farid A Kadyrov
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/1e025a27b5d0423a8048951072262292
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