Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells

Hypoxia promotes tumour aggressiveness and resistance of cancers to oncological treatment. Here, the authors show that caveolin-1 can down-regulate global membrane protein endocytosis in hypoxic cells with potential implications for targeting the hypoxic 3microenvironment of aggressive tumours.

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Autores principales: E. Bourseau-Guilmain, J. A. Menard, E. Lindqvist, V. Indira Chandran, H. C. Christianson, M. Cerezo Magaña, J. Lidfeldt, G. Marko-Varga, C. Welinder, M. Belting
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Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/1e1a53f7a7094b50bafa7b8b8e2815da
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spelling oai:doaj.org-article:1e1a53f7a7094b50bafa7b8b8e2815da2021-12-02T15:34:54ZHypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells10.1038/ncomms113712041-1723https://doaj.org/article/1e1a53f7a7094b50bafa7b8b8e2815da2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11371https://doaj.org/toc/2041-1723Hypoxia promotes tumour aggressiveness and resistance of cancers to oncological treatment. Here, the authors show that caveolin-1 can down-regulate global membrane protein endocytosis in hypoxic cells with potential implications for targeting the hypoxic 3microenvironment of aggressive tumours.E. Bourseau-GuilmainJ. A. MenardE. LindqvistV. Indira ChandranH. C. ChristiansonM. Cerezo MagañaJ. LidfeldtG. Marko-VargaC. WelinderM. BeltingNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
E. Bourseau-Guilmain
J. A. Menard
E. Lindqvist
V. Indira Chandran
H. C. Christianson
M. Cerezo Magaña
J. Lidfeldt
G. Marko-Varga
C. Welinder
M. Belting
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
description Hypoxia promotes tumour aggressiveness and resistance of cancers to oncological treatment. Here, the authors show that caveolin-1 can down-regulate global membrane protein endocytosis in hypoxic cells with potential implications for targeting the hypoxic 3microenvironment of aggressive tumours.
format article
author E. Bourseau-Guilmain
J. A. Menard
E. Lindqvist
V. Indira Chandran
H. C. Christianson
M. Cerezo Magaña
J. Lidfeldt
G. Marko-Varga
C. Welinder
M. Belting
author_facet E. Bourseau-Guilmain
J. A. Menard
E. Lindqvist
V. Indira Chandran
H. C. Christianson
M. Cerezo Magaña
J. Lidfeldt
G. Marko-Varga
C. Welinder
M. Belting
author_sort E. Bourseau-Guilmain
title Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
title_short Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
title_full Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
title_fullStr Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
title_full_unstemmed Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
title_sort hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/1e1a53f7a7094b50bafa7b8b8e2815da
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