Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
Hypoxia promotes tumour aggressiveness and resistance of cancers to oncological treatment. Here, the authors show that caveolin-1 can down-regulate global membrane protein endocytosis in hypoxic cells with potential implications for targeting the hypoxic 3microenvironment of aggressive tumours.
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Nature Portfolio
2016
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oai:doaj.org-article:1e1a53f7a7094b50bafa7b8b8e2815da2021-12-02T15:34:54ZHypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells10.1038/ncomms113712041-1723https://doaj.org/article/1e1a53f7a7094b50bafa7b8b8e2815da2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11371https://doaj.org/toc/2041-1723Hypoxia promotes tumour aggressiveness and resistance of cancers to oncological treatment. Here, the authors show that caveolin-1 can down-regulate global membrane protein endocytosis in hypoxic cells with potential implications for targeting the hypoxic 3microenvironment of aggressive tumours.E. Bourseau-GuilmainJ. A. MenardE. LindqvistV. Indira ChandranH. C. ChristiansonM. Cerezo MagañaJ. LidfeldtG. Marko-VargaC. WelinderM. BeltingNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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Science Q E. Bourseau-Guilmain J. A. Menard E. Lindqvist V. Indira Chandran H. C. Christianson M. Cerezo Magaña J. Lidfeldt G. Marko-Varga C. Welinder M. Belting Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells |
description |
Hypoxia promotes tumour aggressiveness and resistance of cancers to oncological treatment. Here, the authors show that caveolin-1 can down-regulate global membrane protein endocytosis in hypoxic cells with potential implications for targeting the hypoxic 3microenvironment of aggressive tumours. |
format |
article |
author |
E. Bourseau-Guilmain J. A. Menard E. Lindqvist V. Indira Chandran H. C. Christianson M. Cerezo Magaña J. Lidfeldt G. Marko-Varga C. Welinder M. Belting |
author_facet |
E. Bourseau-Guilmain J. A. Menard E. Lindqvist V. Indira Chandran H. C. Christianson M. Cerezo Magaña J. Lidfeldt G. Marko-Varga C. Welinder M. Belting |
author_sort |
E. Bourseau-Guilmain |
title |
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells |
title_short |
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells |
title_full |
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells |
title_fullStr |
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells |
title_full_unstemmed |
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells |
title_sort |
hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/1e1a53f7a7094b50bafa7b8b8e2815da |
work_keys_str_mv |
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