Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses

Relatively well conserved domains of influenza A virus (IAV) proteins are potential candidates for the development of a universal IAV vaccine. Here, Deng et al. combine two such conserved antigens (M2e and HA stalk) in a double-layered protein nanoparticle and show that it protects against divergent...

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Autores principales: Lei Deng, Teena Mohan, Timothy Z. Chang, Gilbert X. Gonzalez, Ye Wang, Young-Man Kwon, Sang-Moo Kang, Richard W. Compans, Julie A. Champion, Bao-Zhong Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1e1b7e376b26409f8f98647986ff3a30
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