Physical Comorbidities are Independently Associated with Higher Rates of Psychiatric Readmission in a Chinese Han Population

Chunyu Yang,1– 4,* Xiaomei Zhong,2,4,* Huarong Zhou,2,4 Zhangying Wu,2,4 Min Zhang,2,4 Yuping Ning1,2,4 1The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 2The Affiliated Brain Hospital of Guangzhou Medical Unive...

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Autores principales:	Yang C, Zhong X, Zhou H, Wu Z, Zhang M, Ning Y
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	psychiatric disorder physical comorbidity readmission survival analysis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/1e1e662b97cd444288c0a58a22eb2bea
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spelling	oai:doaj.org-article:1e1e662b97cd444288c0a58a22eb2bea2021-12-02T03:35:31ZPhysical Comorbidities are Independently Associated with Higher Rates of Psychiatric Readmission in a Chinese Han Population1178-2021https://doaj.org/article/1e1e662b97cd444288c0a58a22eb2bea2020-09-01T00:00:00Zhttps://www.dovepress.com/physical-comorbidities-are-independently-associated-with-higher-rates--peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Chunyu Yang,1– 4,* Xiaomei Zhong,2,4,* Huarong Zhou,2,4 Zhangying Wu,2,4 Min Zhang,2,4 Yuping Ning1,2,4 1The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 2The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China; 3The Third People’s Hospital of Zhongshan, Zhongshan, Guangdong, People’s Republic of China; 4Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuping NingThe Affiliated Brain Hospital of Guangzhou Medical University, Mingxin Road #36, Liwan District, Guangzhou, Guangdong, People’s Republic of ChinaTel +86 20-8126-8720Fax +86 20-8189-1391Email ningjeny@126.comBackground: In people with psychosis, physical comorbidities are highly widespread and leading contributors to the untimely death encountered. Readmission rates in psychiatric patients are very high. Somatic comorbidities could be one of the considerable risk factors for psychiatric rehospitalization. Nevertheless, much less is known about the relation between physical comorbidities and psychiatric readmission. We aimed to investigate the association between physical comorbidities and psychiatric readmission in Han Chinese patients with psychiatric disorders.Methods: We used administrative data for January 1, 2009 to December 31, 2018 from the headquarters of the Affiliated Brain Hospital of Guangzhou Medical University to identify adults with schizophrenia, unipolar depression or bipolar disorder discharged from hospital. Data were extracted on sociodemographic and clinical characteristics. The Charlson comorbidity index (CCI) was used to assess the existence of significant physical comorbidity. Cox proportional hazards regression estimated rehospitalization risk after discharge.Results: A total of 15,620 individuals were included in this study, with the mean age of 35.1 years (SD = 12.8), and readmission occurred for 23.6% of participants. Survival analysis showed that physical comorbidities were statistically and significantly associated with psychiatric readmission, even after the adjustment for the number of psychiatric comorbidities, other sociodemographic and clinical variables.Conclusion: Our results suggest that somatic comorbidities are related with higher rates of psychiatric readmission. Hence, to treat psychosis more effectively and to reduce rehospitalization, it is crucial to treat physical comorbidities promptly and adequately. It is absolutely necessary to bring somatic comorbidities to the forefront of psychiatric treatment and research.Keywords: psychiatric disorder, physical comorbidity, readmission, survival analysisYang CZhong XZhou HWu ZZhang MNing YDove Medical Pressarticlepsychiatric disorderphysical comorbidityreadmissionsurvival analysisNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 16, Pp 2073-2082 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	psychiatric disorder physical comorbidity readmission survival analysis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	psychiatric disorder physical comorbidity readmission survival analysis Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Yang C Zhong X Zhou H Wu Z Zhang M Ning Y Physical Comorbidities are Independently Associated with Higher Rates of Psychiatric Readmission in a Chinese Han Population
description	Chunyu Yang,1– 4,* Xiaomei Zhong,2,4,* Huarong Zhou,2,4 Zhangying Wu,2,4 Min Zhang,2,4 Yuping Ning1,2,4 1The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 2The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China; 3The Third People’s Hospital of Zhongshan, Zhongshan, Guangdong, People’s Republic of China; 4Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuping NingThe Affiliated Brain Hospital of Guangzhou Medical University, Mingxin Road #36, Liwan District, Guangzhou, Guangdong, People’s Republic of ChinaTel +86 20-8126-8720Fax +86 20-8189-1391Email ningjeny@126.comBackground: In people with psychosis, physical comorbidities are highly widespread and leading contributors to the untimely death encountered. Readmission rates in psychiatric patients are very high. Somatic comorbidities could be one of the considerable risk factors for psychiatric rehospitalization. Nevertheless, much less is known about the relation between physical comorbidities and psychiatric readmission. We aimed to investigate the association between physical comorbidities and psychiatric readmission in Han Chinese patients with psychiatric disorders.Methods: We used administrative data for January 1, 2009 to December 31, 2018 from the headquarters of the Affiliated Brain Hospital of Guangzhou Medical University to identify adults with schizophrenia, unipolar depression or bipolar disorder discharged from hospital. Data were extracted on sociodemographic and clinical characteristics. The Charlson comorbidity index (CCI) was used to assess the existence of significant physical comorbidity. Cox proportional hazards regression estimated rehospitalization risk after discharge.Results: A total of 15,620 individuals were included in this study, with the mean age of 35.1 years (SD = 12.8), and readmission occurred for 23.6% of participants. Survival analysis showed that physical comorbidities were statistically and significantly associated with psychiatric readmission, even after the adjustment for the number of psychiatric comorbidities, other sociodemographic and clinical variables.Conclusion: Our results suggest that somatic comorbidities are related with higher rates of psychiatric readmission. Hence, to treat psychosis more effectively and to reduce rehospitalization, it is crucial to treat physical comorbidities promptly and adequately. It is absolutely necessary to bring somatic comorbidities to the forefront of psychiatric treatment and research.Keywords: psychiatric disorder, physical comorbidity, readmission, survival analysis
format	article
author	Yang C Zhong X Zhou H Wu Z Zhang M Ning Y
author_facet	Yang C Zhong X Zhou H Wu Z Zhang M Ning Y
author_sort	Yang C
title	Physical Comorbidities are Independently Associated with Higher Rates of Psychiatric Readmission in a Chinese Han Population
title_short	Physical Comorbidities are Independently Associated with Higher Rates of Psychiatric Readmission in a Chinese Han Population
title_full	Physical Comorbidities are Independently Associated with Higher Rates of Psychiatric Readmission in a Chinese Han Population
title_fullStr	Physical Comorbidities are Independently Associated with Higher Rates of Psychiatric Readmission in a Chinese Han Population
title_full_unstemmed	Physical Comorbidities are Independently Associated with Higher Rates of Psychiatric Readmission in a Chinese Han Population
title_sort	physical comorbidities are independently associated with higher rates of psychiatric readmission in a chinese han population
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/1e1e662b97cd444288c0a58a22eb2bea
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_version_	1718401717412823040

Physical Comorbidities are Independently Associated with Higher Rates of Psychiatric Readmission in a Chinese Han Population

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