Analysis of 180 genetic variants in a new interactive FX variant database reveals novel insights into FX deficiency

Coagulation Factor X (FX), often termed Stuart-Prower Factor, is a plasma glycoprotein composed of the γ-carboxyglutamic acid (Gla) domain, two epidermal growth factor domains (EGF-1, EGF-2) and the serine protease (SP) domain. FX plays a pivotal role in the coagulation cascade, activating thrombin...

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Autores principales: Victoria Anne Harris, Weining Lin, Stephen J Perkins
Formato: article
Lenguaje:EN
Publicado: Georg Thieme Verlag KG 2021
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Acceso en línea:https://doaj.org/article/1e2a4c2c89a245bdb76ed39dac35d95a
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