In type 1 diabetes a subset of anti-coxsackievirus B4 antibodies recognize autoantigens and induce apoptosis of pancreatic beta cells.

In type 1 diabetes a subset of anti-coxsackievirus B4 antibodies recognize autoantigens and induce apoptosis of pancreatic beta cells.

Type 1 diabetes is characterized by autoimmune destruction of pancreatic beta cells. The role played by autoantibodies directed against beta cells antigens in the pathogenesis of the disease is still unclear. Coxsackievirus B infection has been linked to the onset of type 1 diabetes; however its pre...

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Autores principales: Caterina Bason, Renata Lorini, Claudio Lunardi, Marzia Dolcino, Alessandro Giannattasio, Giuseppe d'Annunzio, Antonella Rigo, Nicoletta Pedemonte, Roberto Corrocher, Antonio Puccetti
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1e2aa64c278a464da213aea72d25eac0
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