Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility

Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility

Abstract Non-alcoholic fatty liver disease (NAFLD) constitutes a metabolic disorder with high worldwide prevalence and increasing incidence. The inflammatory progressive state, non-alcoholic steatohepatitis (NASH), leads to liver fibrosis and carcinogenesis. Here, we evaluated whether tyrosinase mut...

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Autores principales: Kaushalya Kulathunga, Arata Wakimoto, Yukiko Hiraishi, Manoj Kumar Yadav, Kyle Gentleman, Eiji Warabi, Tomoki Sakasai, Yoshihiro Miwa, Seiya Mizuno, Satoru Takahashi, Michito Hamada
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1e3d06d303874791b7d8c5107ec033d1
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