Collagenous Enteritis – An Alternative Cause of Malabsorptive Enteropathy

Introduction: Collagenous Enteritis (CE) is a less common cause of enteropathy presenting with malabsorption as its cardinal symptom. While historically considered a resistant form of celiac disease, newer evidence supports the interaction between genetic predispositions and environmental triggers a...

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Autores principales:	Ebrahim Mirakhor, June Choe, Robert Goodman
Formato:	article
Lenguaje:	EN
Publicado:	Shiraz University of Medical Sciences 2021
Materias:	collagenous enteritis malabsorption celiac disease refractory diarrhea Medicine R
Acceso en línea:	https://doaj.org/article/1e577527fd324406bfc2bafcde7cd777
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spelling	oai:doaj.org-article:1e577527fd324406bfc2bafcde7cd7772021-11-14T06:50:42ZCollagenous Enteritis – An Alternative Cause of Malabsorptive Enteropathy2783-243010.30476/acrr.2021.91296.1100https://doaj.org/article/1e577527fd324406bfc2bafcde7cd7772021-06-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_47686_c78143afbbbaf7d1ee895706d9901cf3.pdfhttps://doaj.org/toc/2783-2430Introduction: Collagenous Enteritis (CE) is a less common cause of enteropathy presenting with malabsorption as its cardinal symptom. While historically considered a resistant form of celiac disease, newer evidence supports the interaction between genetic predispositions and environmental triggers as the pathophysiologic basis of CE. Case Presentation: Herein we present the case of a 40-year-old woman with two-year history of diarrhea and 32 kg weight loss who was incorrectly diagnosed with celiac disease with refractory symptoms despite adherence to a gluten-free diet. Extensive infectious, inflammatory, secretory, autoimmune workup did not reveal an underlying etiology. Endoscopic evidence of severe villous blunting and biopsy with characteristic patchy enlarged subepithelial collagen layer solidified a diagnosis of CE. Treatment with steroids resulted in resolution of malabsorptive symptoms and gradual weight gain. Conclusion: This case highlights the importance of considering CE in patients presenting with malabsorption especially given significant clinical overlap with other malasbsorptive conditions as well as its therapeutic implications.Ebrahim MirakhorJune ChoeRobert GoodmanShiraz University of Medical Sciencesarticlecollagenous enteritismalabsorptionceliac diseaserefractory diarrheaMedicineRENIranian Journal of Colorectal Research, Vol 9, Iss 2, Pp 78-81 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	collagenous enteritis malabsorption celiac disease refractory diarrhea Medicine R
spellingShingle	collagenous enteritis malabsorption celiac disease refractory diarrhea Medicine R Ebrahim Mirakhor June Choe Robert Goodman Collagenous Enteritis – An Alternative Cause of Malabsorptive Enteropathy
description	Introduction: Collagenous Enteritis (CE) is a less common cause of enteropathy presenting with malabsorption as its cardinal symptom. While historically considered a resistant form of celiac disease, newer evidence supports the interaction between genetic predispositions and environmental triggers as the pathophysiologic basis of CE. Case Presentation: Herein we present the case of a 40-year-old woman with two-year history of diarrhea and 32 kg weight loss who was incorrectly diagnosed with celiac disease with refractory symptoms despite adherence to a gluten-free diet. Extensive infectious, inflammatory, secretory, autoimmune workup did not reveal an underlying etiology. Endoscopic evidence of severe villous blunting and biopsy with characteristic patchy enlarged subepithelial collagen layer solidified a diagnosis of CE. Treatment with steroids resulted in resolution of malabsorptive symptoms and gradual weight gain. Conclusion: This case highlights the importance of considering CE in patients presenting with malabsorption especially given significant clinical overlap with other malasbsorptive conditions as well as its therapeutic implications.
format	article
author	Ebrahim Mirakhor June Choe Robert Goodman
author_facet	Ebrahim Mirakhor June Choe Robert Goodman
author_sort	Ebrahim Mirakhor
title	Collagenous Enteritis – An Alternative Cause of Malabsorptive Enteropathy
title_short	Collagenous Enteritis – An Alternative Cause of Malabsorptive Enteropathy
title_full	Collagenous Enteritis – An Alternative Cause of Malabsorptive Enteropathy
title_fullStr	Collagenous Enteritis – An Alternative Cause of Malabsorptive Enteropathy
title_full_unstemmed	Collagenous Enteritis – An Alternative Cause of Malabsorptive Enteropathy
title_sort	collagenous enteritis – an alternative cause of malabsorptive enteropathy
publisher	Shiraz University of Medical Sciences
publishDate	2021
url	https://doaj.org/article/1e577527fd324406bfc2bafcde7cd777
work_keys_str_mv	AT ebrahimmirakhor collagenousenteritisanalternativecauseofmalabsorptiveenteropathy AT junechoe collagenousenteritisanalternativecauseofmalabsorptiveenteropathy AT robertgoodman collagenousenteritisanalternativecauseofmalabsorptiveenteropathy
_version_	1718429821604724736

Collagenous Enteritis – An Alternative Cause of Malabsorptive Enteropathy

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