Anticancer activity and antibody-dependent cell-mediated cytotoxicity of novel anti-nucleolin antibodies
Abstract Nucleolin arises as a relevant target for cancer therapy, as it is overexpressed at the surface of cancer and angiogenic endothelial cells thus enabling a dual cellular targeting strategy. Immunotherapeutic strategies, albeit of proven therapeutic relevance, have been scarcely explored agai...
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Autores principales: | Sofia Romano, Vera Moura, Sérgio Simões, João Nuno Moreira, João Gonçalves |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/1e57d1ee92984485a418010f2f6800b3 |
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