DYNAMICS OF SERUM IMMUNOGLOBULINS IN ONCOLOGICAL PATIENTS DURING PERIOPERATIVE PERIOD

The aim of the study was to investigate the dynamics of serum immunoglobulins from oncological patients in the perioperative period. As a result of investigations, it was established that already at the initial stage of the intraoperative period the IgM concentration was elevated in patients' s...

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Autores principales: N. A. Pluzhnikova, N. Yu. Anisimova, O. V. Lebedinskaya, D. S. Tsvetkov, A. P. Godovalov, M. V. Kiselevsky
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2012
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Acceso en línea:https://doaj.org/article/1e58fe11990b49058c51ff2c19c36aab
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Sumario:The aim of the study was to investigate the dynamics of serum immunoglobulins from oncological patients in the perioperative period. As a result of investigations, it was established that already at the initial stage of the intraoperative period the IgM concentration was elevated in patients' sera, and persisted up to 3 days after surgical intervention, while exceeding the values of the control group by 30—80 %. At the same time, no significant changes were detected in IgA and IgG levels of examined patients in the perioperative period. The obtained data confirm the expediency of carrying out the monitoring of immunoglobulin levels in oncological patients both in intra-, and postoperative periods and can be used for the assessment of patient's immune status and in the choice of immunocorrecting therapy strategy.