Physiologically based pharmacokinetic modeling of PLGA nanoparticles with varied mPEG content

Código QR

Physiologically based pharmacokinetic modeling of PLGA nanoparticles with varied mPEG content

Mingguang Li1, Zoi Panagi2, Konstantinos Avgoustakis2, Joshua Reineke11Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA; 2Pharmaceutical Technology Laboratory, Department of Pharmacy, University of Patras, Rion,...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Avgoustakis K, Li M, Panagi Z, Reineke J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/1e60d02656114967bef0b34f08254c2c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Codelivery of SH-aspirin and curcumin by mPEG-PLGA nanoparticles enhanced antitumor activity by inducing mitochondrial apoptosis
por: Zhou L, et al.
Publicado: (2015)

Mithramycin-loaded mPEG-PLGA nanoparticles exert potent antitumor efficacy against pancreatic carcinoma
por: Liu XJ, et al.
Publicado: (2017)

Rhynchophylline Loaded-mPEG-PLGA Nanoparticles Coated with Tween-80 for Preliminary Study in Alzheimer’s Disease
por: Xu R, et al.
Publicado: (2020)

Bufalin-loaded mPEG-PLGA-PLL-cRGD nanoparticles: preparation, cellular uptake, tissue distribution, and anticancer activity
por: Duan YR, et al.
Publicado: (2012)

Degradability, bioactivity, and osteogenesis of biocomposite scaffolds of lithium-containing mesoporous bioglass and mPEG-PLGA-b-PLL copolymer
por: Cai Y, et al.
Publicado: (2015)

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile
por: Rafiei P, et al.
Publicado: (2017)

Synthesis, characterization, and evaluation of mPEG–SN38 and mPEG–PLA–SN38 micelles for cancer therapy
por: Xie J, et al.
Publicado: (2016)

Effects of pH-sensitive chain length on release of doxorubicin from mPEG-b-PH-b-PLLA nanoparticles
por: Liu R, et al.
Publicado: (2012)

Improving aqueous solubility and antitumor effects by nanosized gambogic acid-mPEG2000 micelles
por: Cai LL, et al.
Publicado: (2013)

Endostar-loaded PEG-PLGA nanoparticles: in vitro and in vivo evaluation
por: Sanyuan Hu, et al.
Publicado: (2010)

Elaboration and characterization of curcumin-loaded Tri-CL-mPEG three-arm copolymeric nanoparticles by a microchannel technology
por: Wu W, et al.
Publicado: (2019)

mPEG-PLA/TPGS mixed micelles via intranasal administration improved the bioavailability of lamotrigine in the hippocampus
por: Yu A, et al.
Publicado: (2017)

Artemisinin Loaded mPEG-PCL Nanoparticle Based Photosensitive Gelatin Methacrylate Hydrogels for the Treatment of Gentamicin Induced Hearing Loss
por: Li X, et al.
Publicado: (2020)

Enhancement of tumor tropism of mPEGylated nanoparticles by anti-mPEG bispecific antibody for ovarian cancer therapy
por: Wen-Wei Lin, et al.
Publicado: (2021)

Neuroprotective effect of insulin-loaded chitosan nanoparticles/PLGA-PEG-PLGA hydrogel on diabetic retinopathy in rats
por: Rong X, et al.
Publicado: (2018)

Micellar emulsions composed of mPEG-PCL/MCT as novel nanocarriers for systemic delivery of genistein: a comparative study with micelles
por: Zhang TP, et al.
Publicado: (2015)

Preparation and in vivo pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles
por: Feng R, et al.
Publicado: (2012)

10-Hydroxycamptothecin (HCPT) nanosuspensions stabilized by mPEG1000-HCPT conjugate: high stabilizing efficiency and improved antitumor efficacy
por: Yang L, et al.
Publicado: (2017)

A physiologically based pharmacokinetic model for ionic silver and silver nanoparticles
por: Bachler G, et al.
Publicado: (2013)

pH and temperature dual-sensitive liposome gel based on novel cleavable mPEG-Hz-CHEMS polymeric vaginal delivery system
por: Chen D, et al.
Publicado: (2012)

Trastuzumab- and Fab′ fragment-modified curcumin PEG-PLGA nanoparticles: preparation and evaluation in vitro and in vivo
por: Duan D, et al.
Publicado: (2018)

Physiologically based pharmacokinetic modeling of zinc oxide nanoparticles and zinc nitrate in mice
por: Chen WY, et al.
Publicado: (2015)

Shape dependent cytotoxicity of PLGA-PEG nanoparticles on human cells
por: Bokai Zhang, et al.
Publicado: (2017)

Self-assembled mPEG&ndash;PCL-g&ndash;PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro
por: Shi S, et al.
Publicado: (2012)

Effects of PEG surface density and chain length on the pharmacokinetics and biodistribution of methotrexate-loaded chitosan nanoparticles
por: Ait Bachir Z, et al.
Publicado: (2018)

Effects of a novel pH-sensitive liposome with cleavable esterase-catalyzed and pH-responsive double smart mPEG lipid derivative on ABC phenomenon
por: Chen D, et al.
Publicado: (2011)

Intranasal delivery of rotigotine to the brain with lactoferrin-modified PEG-PLGA nanoparticles for Parkinson’s disease treatment
por: Bi CC, et al.
Publicado: (2016)

Toward a general physiologically-based pharmacokinetic model for intravenously injected nanoparticles
por: Carlander U, et al.
Publicado: (2016)

PLGA-PLL-PEG-Tf-based targeted nanoparticles drug delivery system enhance antitumor efficacy via intrinsic apoptosis pathway
por: Bao W, et al.
Publicado: (2015)

Preparation of sustained release apremilast-loaded PLGA nanoparticles: in vitro characterization and in vivo pharmacokinetic study in rats
por: Anwer MK, et al.
Publicado: (2019)

Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells
por: Li L, et al.
Publicado: (2014)

Formulation of tunable size PLGA-PEG nanoparticles for drug delivery using microfluidic technology.
por: Adrianna Glinkowska Mares, et al.
Publicado: (2021)

Role of hydroxypropyl-&beta;-cyclodextrin on freeze-dried and gamma-irradiated PLGA and PLGA&ndash;PEG diblock copolymer nanospheres for ophthalmic flurbiprofen delivery
por: Vega E, et al.
Publicado: (2012)

pH-sensitive and folic acid-targeted MPEG-PHIS/FA-PEG-VE mixed micelles for the delivery of PTX-VE and their antitumor activity
por: Di Y, et al.
Publicado: (2017)

Targeted delivery by pH-responsive mPEG-S-PBLG micelles significantly enhances the anti-tumor efficacy of doxorubicin with reduced cardiotoxicity
por: Qiyi Feng, et al.
Publicado: (2021)

Eudragit®-S100 Coated PLGA Nanoparticles for Colon Targeting of Etoricoxib: Optimization and Pharmacokinetic Assessments in Healthy Human Volunteers
por: El-Maghawry E, et al.
Publicado: (2020)

Targeted multidrug-resistance reversal in tumor based on PEG-PLL-PLGA polymer nano drug delivery system
por: Guo L, et al.
Publicado: (2015)

Pigment epithelial-derived factor gene loaded novel COOH-PEG-PLGA-COOH nanoparticles promoted tumor suppression by systemic administration
por: Yu T, et al.
Publicado: (2016)

Preventing postoperative abdominal adhesions in a rat model with PEG-PCL-PEG hydrogel
por: Yang B, et al.
Publicado: (2012)

Optimization, Characterization and Pharmacokinetic Study of Meso-Tetraphenylporphyrin Metal Complex-Loaded PLGA Nanoparticles
por: Mariia R. Mollaeva, et al.
Publicado: (2021)