Synergistic effects of polyphenols and methylxanthines with Leucine on AMPK/Sirtuin-mediated metabolism in muscle cells and adipocytes.
The AMPK-Sirt1 pathway is an important regulator of energy metabolism and therefore a potential target for prevention and therapy of metabolic diseases. We recently demonstrated leucine and its metabolite β-hydroxy-β-methylbutyrate (HMB) to synergize with low-dose resveratrol (200 nM) to activate si...
Guardado en:
Autores principales: | Antje Bruckbauer, Michael B Zemel |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1e6884b466ee484684ad90c38059d9fd |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Effects of a leucine and pyridoxine-containing nutraceutical on body weight and composition in obese subjects
por: Zemel MB, et al.
Publicado: (2013) -
Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity
por: Bruckbauer A, et al.
Publicado: (2013) -
Interaction between leucine and phosphodiesterase 5 inhibition in modulating insulin sensitivity and lipid metabolism
por: Fu L, et al.
Publicado: (2015) -
Sirtuins as Metabolic Regulators of Immune Cells Phenotype and Function
por: Lídia Fortuny, et al.
Publicado: (2021) -
Towards Splicing Therapy for Lysosomal Storage Disorders: Methylxanthines and Luteolin Ameliorate Splicing Defects in Aspartylglucosaminuria and Classic Late Infantile Neuronal Ceroid Lipofuscinosis
por: Antje Banning, et al.
Publicado: (2021)