Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep

Despite evidence that astrocytes mediate sleep-dependent function, the involved signaling mechanisms are unknown. The authors show that astrocytic Ca2+ signalling exhibits distinct features across the sleep-wake cycle and ablation of this Ca2+ signalling pathway impairs slow wave sleep.

Guardado en:

Detalles Bibliográficos
Autores principales:	Laura Bojarskaite, Daniel M. Bjørnstad, Klas H. Pettersen, Céline Cunen, Gudmund Horn Hermansen, Knut Sindre Åbjørsbråten, Anna R. Chambers, Rolf Sprengel, Koen Vervaeke, Wannan Tang, Rune Enger, Erlend A. Nagelhus
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1e68c981b1e04846bd23cd2939be5062
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1e68c981b1e04846bd23cd2939be5062
record_format	dspace
spelling	oai:doaj.org-article:1e68c981b1e04846bd23cd2939be50622021-12-02T18:33:59ZAstrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep10.1038/s41467-020-17062-22041-1723https://doaj.org/article/1e68c981b1e04846bd23cd2939be50622020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17062-2https://doaj.org/toc/2041-1723Despite evidence that astrocytes mediate sleep-dependent function, the involved signaling mechanisms are unknown. The authors show that astrocytic Ca2+ signalling exhibits distinct features across the sleep-wake cycle and ablation of this Ca2+ signalling pathway impairs slow wave sleep.Laura BojarskaiteDaniel M. BjørnstadKlas H. PettersenCéline CunenGudmund Horn HermansenKnut Sindre ÅbjørsbråtenAnna R. ChambersRolf SprengelKoen VervaekeWannan TangRune EngerErlend A. NagelhusNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Laura Bojarskaite Daniel M. Bjørnstad Klas H. Pettersen Céline Cunen Gudmund Horn Hermansen Knut Sindre Åbjørsbråten Anna R. Chambers Rolf Sprengel Koen Vervaeke Wannan Tang Rune Enger Erlend A. Nagelhus Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
description	Despite evidence that astrocytes mediate sleep-dependent function, the involved signaling mechanisms are unknown. The authors show that astrocytic Ca2+ signalling exhibits distinct features across the sleep-wake cycle and ablation of this Ca2+ signalling pathway impairs slow wave sleep.
format	article
author	Laura Bojarskaite Daniel M. Bjørnstad Klas H. Pettersen Céline Cunen Gudmund Horn Hermansen Knut Sindre Åbjørsbråten Anna R. Chambers Rolf Sprengel Koen Vervaeke Wannan Tang Rune Enger Erlend A. Nagelhus
author_facet	Laura Bojarskaite Daniel M. Bjørnstad Klas H. Pettersen Céline Cunen Gudmund Horn Hermansen Knut Sindre Åbjørsbråten Anna R. Chambers Rolf Sprengel Koen Vervaeke Wannan Tang Rune Enger Erlend A. Nagelhus
author_sort	Laura Bojarskaite
title	Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
title_short	Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
title_full	Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
title_fullStr	Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
title_full_unstemmed	Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
title_sort	astrocytic ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/1e68c981b1e04846bd23cd2939be5062
work_keys_str_mv	AT laurabojarskaite astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep AT danielmbjørnstad astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep AT klashpettersen astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep AT celinecunen astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep AT gudmundhornhermansen astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep AT knutsindreabjørsbraten astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep AT annarchambers astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep AT rolfsprengel astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep AT koenvervaeke astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep AT wannantang astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep AT runeenger astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep AT erlendanagelhus astrocyticca2signalingisreducedduringsleepandisinvolvedintheregulationofslowwavesleep
_version_	1718377905954750464

Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep

Ejemplares similares