Pro-inflammatory role of NLRP3 inflammasome in experimental sterile corneal inflammation

Abstract We evaluated the role of NLR family pyrin domain containing 3 (NLRP3) inflammasome in sterile corneal inflammation caused by lipopolysaccharide (LPS) or alkali burns in C57BL6 mice or NLRP3 KO (Nlrp3 −/− ) mice. Various molecules related to the NLRP3 inflammasome were upregulated in C57BL6...

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Autores principales: Hiroaki Shimizu, Tohru Sakimoto, Satoru Yamagami
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1e6d012662cf4412b5caad81d7c2418a
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