Quantification of visual field loss in age-related macular degeneration.

<h4>Background</h4>An evaluation of standard automated perimetry (SAP) and short wavelength automated perimetry (SWAP) for the central 10-2 visual field test procedure in patients with age-related macular degeneration (AMD) is presented in order to determine methods of quantifying the ce...

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Autores principales:	Jennifer H Acton, Jonathan M Gibson, Robert P Cubbidge
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/1e73f8978773495989e8558ac16ed23d
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id	oai:doaj.org-article:1e73f8978773495989e8558ac16ed23d
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spelling	oai:doaj.org-article:1e73f8978773495989e8558ac16ed23d2021-11-18T07:13:49ZQuantification of visual field loss in age-related macular degeneration.1932-620310.1371/journal.pone.0039944https://doaj.org/article/1e73f8978773495989e8558ac16ed23d2012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22768178/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>An evaluation of standard automated perimetry (SAP) and short wavelength automated perimetry (SWAP) for the central 10-2 visual field test procedure in patients with age-related macular degeneration (AMD) is presented in order to determine methods of quantifying the central sensitivity loss in patients at various stages of AMD.<h4>Methods</h4>10-2 SAP and SWAP Humphrey visual fields and stereoscopic fundus photographs were collected in 27 eyes of 27 patients with AMD and 22 eyes of 22 normal subjects.<h4>Results</h4>Mean Deviation and Pattern Standard Deviation (PSD) varied significantly with stage of disease in SAP (both p<0.001) and SWAP (both p<0.001), but post hoc analysis revealed overlap of functional values among stages. In SWAP, indices of focal loss were more sensitive to detecting differences in AMD from normal. SWAP defects were greater in depth and area than those in SAP. Central sensitivity (within 1°) changed by -3.9 and -4.9 dB per stage in SAP and SWAP, respectively. Based on defect maps, an AMD Severity Index was derived.<h4>Conclusions</h4>Global indices of focal loss were more sensitive to detecting early stage AMD from normal. The SWAP sensitivity decline with advancing stage of AMD was greater than in SAP. A new AMD Severity Index quantifies visual field defects on a continuous scale. Although not all patients are suitable for SWAP examinations, it is of value as a tool in research studies of visual loss in AMD.Jennifer H ActonJonathan M GibsonRobert P CubbidgePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 6, p e39944 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jennifer H Acton Jonathan M Gibson Robert P Cubbidge Quantification of visual field loss in age-related macular degeneration.
description	<h4>Background</h4>An evaluation of standard automated perimetry (SAP) and short wavelength automated perimetry (SWAP) for the central 10-2 visual field test procedure in patients with age-related macular degeneration (AMD) is presented in order to determine methods of quantifying the central sensitivity loss in patients at various stages of AMD.<h4>Methods</h4>10-2 SAP and SWAP Humphrey visual fields and stereoscopic fundus photographs were collected in 27 eyes of 27 patients with AMD and 22 eyes of 22 normal subjects.<h4>Results</h4>Mean Deviation and Pattern Standard Deviation (PSD) varied significantly with stage of disease in SAP (both p<0.001) and SWAP (both p<0.001), but post hoc analysis revealed overlap of functional values among stages. In SWAP, indices of focal loss were more sensitive to detecting differences in AMD from normal. SWAP defects were greater in depth and area than those in SAP. Central sensitivity (within 1°) changed by -3.9 and -4.9 dB per stage in SAP and SWAP, respectively. Based on defect maps, an AMD Severity Index was derived.<h4>Conclusions</h4>Global indices of focal loss were more sensitive to detecting early stage AMD from normal. The SWAP sensitivity decline with advancing stage of AMD was greater than in SAP. A new AMD Severity Index quantifies visual field defects on a continuous scale. Although not all patients are suitable for SWAP examinations, it is of value as a tool in research studies of visual loss in AMD.
format	article
author	Jennifer H Acton Jonathan M Gibson Robert P Cubbidge
author_facet	Jennifer H Acton Jonathan M Gibson Robert P Cubbidge
author_sort	Jennifer H Acton
title	Quantification of visual field loss in age-related macular degeneration.
title_short	Quantification of visual field loss in age-related macular degeneration.
title_full	Quantification of visual field loss in age-related macular degeneration.
title_fullStr	Quantification of visual field loss in age-related macular degeneration.
title_full_unstemmed	Quantification of visual field loss in age-related macular degeneration.
title_sort	quantification of visual field loss in age-related macular degeneration.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/1e73f8978773495989e8558ac16ed23d
work_keys_str_mv	AT jenniferhacton quantificationofvisualfieldlossinagerelatedmaculardegeneration AT jonathanmgibson quantificationofvisualfieldlossinagerelatedmaculardegeneration AT robertpcubbidge quantificationofvisualfieldlossinagerelatedmaculardegeneration
_version_	1718423712620871680

Quantification of visual field loss in age-related macular degeneration.

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