The role of asenapine in the treatment of manic or mixed states associated with bipolar I disorder
Maurizio Pompili1,2, Paola Venturini1, Marco Innamorati1, Gianluca Serafini1, Ludovica Telesforo1, David Lester3, Roberto Tatarelli1, Paolo Girardi11Department of Neurosciences, Mental Health and Sensory Functions, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of R...
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Dove Medical Press
2011
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oai:doaj.org-article:1e7894ae2a7c438c9f7cc8c8b22ab13d2021-12-02T02:48:23ZThe role of asenapine in the treatment of manic or mixed states associated with bipolar I disorder1176-63281178-2021https://doaj.org/article/1e7894ae2a7c438c9f7cc8c8b22ab13d2011-05-01T00:00:00Zhttp://www.dovepress.com/the-role-of-asenapine-in-the-treatment-of-manic-or-mixed-states-associ-a7353https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Maurizio Pompili1,2, Paola Venturini1, Marco Innamorati1, Gianluca Serafini1, Ludovica Telesforo1, David Lester3, Roberto Tatarelli1, Paolo Girardi11Department of Neurosciences, Mental Health and Sensory Functions, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy; 2McLean Hospital, Harvard Medical School, Boston, MA, USA; 3The Richard Stockton College of New Jersey, Pomona, NJ, USABackground: Bipolar disorders (BD) are of particular public health significance as they are prevalent, severe and disabling, and often associated with elevated risks of premature mortality. The aim of this concise overview is to investigate the role of asenapine in the treatment of manic and mixed states associated with BD type 1 disorder.Method: MedLine, Excerpta Medica and PsycINFO searches were performed to identify papers in English published over the past 7 years. Search terms were "asenapine", "manic" OR "mixed states", "bipolar I disorder". Subjects included in this study suffered from BD type 1 disorder.Results: To date, only four studies of asenapine for the treatment of manic or mixed episodes associated with BD type 1 have been published.Conclusion: Research indicates that asenapine is generally well-tolerated, and that asenapine is efficacious and not inferior to olanzapine in the treatment of mixed or manic episodes associated with BD type 1 in the short-term and long-term.Keywords: asenapine, bipolar disorder, side effectsPompili MVenturini PInnamorati MSerafini GTelesforo LLester DTatarelli RGirardi PDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2011, Iss Issue 1, Pp 259-265 (2011) |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Pompili M Venturini P Innamorati M Serafini G Telesforo L Lester D Tatarelli R Girardi P The role of asenapine in the treatment of manic or mixed states associated with bipolar I disorder |
| description |
Maurizio Pompili1,2, Paola Venturini1, Marco Innamorati1, Gianluca Serafini1, Ludovica Telesforo1, David Lester3, Roberto Tatarelli1, Paolo Girardi11Department of Neurosciences, Mental Health and Sensory Functions, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy; 2McLean Hospital, Harvard Medical School, Boston, MA, USA; 3The Richard Stockton College of New Jersey, Pomona, NJ, USABackground: Bipolar disorders (BD) are of particular public health significance as they are prevalent, severe and disabling, and often associated with elevated risks of premature mortality. The aim of this concise overview is to investigate the role of asenapine in the treatment of manic and mixed states associated with BD type 1 disorder.Method: MedLine, Excerpta Medica and PsycINFO searches were performed to identify papers in English published over the past 7 years. Search terms were "asenapine", "manic" OR "mixed states", "bipolar I disorder". Subjects included in this study suffered from BD type 1 disorder.Results: To date, only four studies of asenapine for the treatment of manic or mixed episodes associated with BD type 1 have been published.Conclusion: Research indicates that asenapine is generally well-tolerated, and that asenapine is efficacious and not inferior to olanzapine in the treatment of mixed or manic episodes associated with BD type 1 in the short-term and long-term.Keywords: asenapine, bipolar disorder, side effects |
| format |
article |
| author |
Pompili M Venturini P Innamorati M Serafini G Telesforo L Lester D Tatarelli R Girardi P |
| author_facet |
Pompili M Venturini P Innamorati M Serafini G Telesforo L Lester D Tatarelli R Girardi P |
| author_sort |
Pompili M |
| title |
The role of asenapine in the treatment of manic or mixed states associated with bipolar I disorder |
| title_short |
The role of asenapine in the treatment of manic or mixed states associated with bipolar I disorder |
| title_full |
The role of asenapine in the treatment of manic or mixed states associated with bipolar I disorder |
| title_fullStr |
The role of asenapine in the treatment of manic or mixed states associated with bipolar I disorder |
| title_full_unstemmed |
The role of asenapine in the treatment of manic or mixed states associated with bipolar I disorder |
| title_sort |
role of asenapine in the treatment of manic or mixed states associated with bipolar i disorder |
| publisher |
Dove Medical Press |
| publishDate |
2011 |
| url |
https://doaj.org/article/1e7894ae2a7c438c9f7cc8c8b22ab13d |
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