Ocular hypertension after intravitreal triamcinolone with vitrectomy and phacoemulsification

D Wilkin Parke III, Robert A Sisk, Samuel K Houston, Timothy G MurrayDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USAObjective: To evaluate the effect of adjunctive intravitreal triamcinolone (IVTA) on intraocular pressure (IOP)...

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Autores principales: Parke III DW, Sisk RA, Houston SK, Murray TG
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Publicado: Dove Medical Press 2012
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spelling oai:doaj.org-article:1e7c9816aa4b4bc4a2604da2b6d49dfe2021-12-02T01:36:27ZOcular hypertension after intravitreal triamcinolone with vitrectomy and phacoemulsification1177-54671177-5483https://doaj.org/article/1e7c9816aa4b4bc4a2604da2b6d49dfe2012-06-01T00:00:00Zhttp://www.dovepress.com/ocular-hypertension-after-intravitreal-triamcinolone-with-vitrectomy-a-a10141https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483D Wilkin Parke III, Robert A Sisk, Samuel K Houston, Timothy G MurrayDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USAObjective: To evaluate the effect of adjunctive intravitreal triamcinolone (IVTA) on intraocular pressure (IOP) in the setting of combined vitrectomy with phacoemulsification.Design: Retrospective case series.Participants: One hundred thirty-one consecutive eyes undergoing nonemergent vitrectomy with phacoemulsification and IVTA were reviewed and included in the analysis. All 131 eyes received 4 mg IVTA at the end of surgery.Methods: Pre- and postoperative IOP, use of pressure-lowering medications, and rate of glaucoma surgery were analyzed. Pre-operative risk factors were analyzed.Main outcome measures: IOP, glaucoma medications, or glaucoma surgery.Results: Secondary ocular hypertension (defined as IOP ≥25 mmHg) was found in 28 eyes (21%), the majority during postoperative day 1 only. Twelve eyes (9%) had an elevated IOP measurement noted at a visit after the first postoperative day. Five (4%) had an IOP rise of ≥10 mmHg over baseline at any time after postoperative day 1. Six (5%) required glaucoma medications. One eye required a glaucoma drainage implant for diabetic neovascular angle closure glaucoma, and one eye required enucleation for intractable neovascular glaucoma due to radiation retinopathy. Elevated postoperative IOP was statistically associated with higher baseline IOP and presence of preoperative glaucoma.Conclusions: Therapeutic intravitreal triamcinolone with combined vitrectomy and phacoemulsification causes infrequent and usually mild secondary ocular hypertension. Secondary ocular hypertension is associated with preoperative glaucoma and high IOP.Keywords: glaucoma, cataract, inflammationParke III DWSisk RAHouston SKMurray TGDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 925-931 (2012)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Parke III DW
Sisk RA
Houston SK
Murray TG
Ocular hypertension after intravitreal triamcinolone with vitrectomy and phacoemulsification
description D Wilkin Parke III, Robert A Sisk, Samuel K Houston, Timothy G MurrayDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USAObjective: To evaluate the effect of adjunctive intravitreal triamcinolone (IVTA) on intraocular pressure (IOP) in the setting of combined vitrectomy with phacoemulsification.Design: Retrospective case series.Participants: One hundred thirty-one consecutive eyes undergoing nonemergent vitrectomy with phacoemulsification and IVTA were reviewed and included in the analysis. All 131 eyes received 4 mg IVTA at the end of surgery.Methods: Pre- and postoperative IOP, use of pressure-lowering medications, and rate of glaucoma surgery were analyzed. Pre-operative risk factors were analyzed.Main outcome measures: IOP, glaucoma medications, or glaucoma surgery.Results: Secondary ocular hypertension (defined as IOP ≥25 mmHg) was found in 28 eyes (21%), the majority during postoperative day 1 only. Twelve eyes (9%) had an elevated IOP measurement noted at a visit after the first postoperative day. Five (4%) had an IOP rise of ≥10 mmHg over baseline at any time after postoperative day 1. Six (5%) required glaucoma medications. One eye required a glaucoma drainage implant for diabetic neovascular angle closure glaucoma, and one eye required enucleation for intractable neovascular glaucoma due to radiation retinopathy. Elevated postoperative IOP was statistically associated with higher baseline IOP and presence of preoperative glaucoma.Conclusions: Therapeutic intravitreal triamcinolone with combined vitrectomy and phacoemulsification causes infrequent and usually mild secondary ocular hypertension. Secondary ocular hypertension is associated with preoperative glaucoma and high IOP.Keywords: glaucoma, cataract, inflammation
format article
author Parke III DW
Sisk RA
Houston SK
Murray TG
author_facet Parke III DW
Sisk RA
Houston SK
Murray TG
author_sort Parke III DW
title Ocular hypertension after intravitreal triamcinolone with vitrectomy and phacoemulsification
title_short Ocular hypertension after intravitreal triamcinolone with vitrectomy and phacoemulsification
title_full Ocular hypertension after intravitreal triamcinolone with vitrectomy and phacoemulsification
title_fullStr Ocular hypertension after intravitreal triamcinolone with vitrectomy and phacoemulsification
title_full_unstemmed Ocular hypertension after intravitreal triamcinolone with vitrectomy and phacoemulsification
title_sort ocular hypertension after intravitreal triamcinolone with vitrectomy and phacoemulsification
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/1e7c9816aa4b4bc4a2604da2b6d49dfe
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AT houstonsk ocularhypertensionafterintravitrealtriamcinolonewithvitrectomyandphacoemulsification
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