Preclinical immunogenicity testing using anti-drug antibody analysis of GX-G3, Fc-fused recombinant human granulocyte colony-stimulating factor, in rat and monkey models
Abstract Human granulocyte colony-stimulating factor (G-CSF, this study used Fc-fused recombinant G-CSF; GX-G3) is an important glycoprotein that stimulates the proliferation of granulocytes and white blood cells. Thus, G-CSF treatment has been considered as a crucial regimen to accelerate recovery...
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Main Authors: | Yun Jung Kim, Eun Mi Koh, Chi Hun Song, Mi Sun Byun, Yu Ri Choi, Eun-Jeong Jeon, Kyunghwa Hwang, Sang Kyum Kim, Sang In Yang, Kyung Jin Jung |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/1e7e1b8db8614df985eda9ab5846fc92 |
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