Preclinical immunogenicity testing using anti-drug antibody analysis of GX-G3, Fc-fused recombinant human granulocyte colony-stimulating factor, in rat and monkey models

Abstract Human granulocyte colony-stimulating factor (G-CSF, this study used Fc-fused recombinant G-CSF; GX-G3) is an important glycoprotein that stimulates the proliferation of granulocytes and white blood cells. Thus, G-CSF treatment has been considered as a crucial regimen to accelerate recovery...

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Autores principales: Yun Jung Kim, Eun Mi Koh, Chi Hun Song, Mi Sun Byun, Yu Ri Choi, Eun-Jeong Jeon, Kyunghwa Hwang, Sang Kyum Kim, Sang In Yang, Kyung Jin Jung
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1e7e1b8db8614df985eda9ab5846fc92
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