Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy

Quantification of intratumoral nanoparticles internalisation in vivo is crucial but challenging. Here, the authors develop a binary ratiometric nanoreporter that can quantify internalisation and predict nanotherapeutic responses based on intracellular nanoparticle exposure.

Guardado en:
Detalles Bibliográficos
Autores principales: Qingqing Yin, Anni Pan, Binlong Chen, Zenghui Wang, Mingmei Tang, Yue Yan, Yaoqi Wang, Heming Xia, Wei Chen, Hongliang Du, Meifang Chen, Chuanxun Fu, Yanni Wang, Xia Yuan, Zhihao Lu, Qiang Zhang, Yiguang Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/1e83db7f66c14a24885a735e9e8fd609
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Quantification of intratumoral nanoparticles internalisation in vivo is crucial but challenging. Here, the authors develop a binary ratiometric nanoreporter that can quantify internalisation and predict nanotherapeutic responses based on intracellular nanoparticle exposure.