Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy

Quantification of intratumoral nanoparticles internalisation in vivo is crucial but challenging. Here, the authors develop a binary ratiometric nanoreporter that can quantify internalisation and predict nanotherapeutic responses based on intracellular nanoparticle exposure.

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Autores principales:	Qingqing Yin, Anni Pan, Binlong Chen, Zenghui Wang, Mingmei Tang, Yue Yan, Yaoqi Wang, Heming Xia, Wei Chen, Hongliang Du, Meifang Chen, Chuanxun Fu, Yanni Wang, Xia Yuan, Zhihao Lu, Qiang Zhang, Yiguang Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1e83db7f66c14a24885a735e9e8fd609
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spelling	oai:doaj.org-article:1e83db7f66c14a24885a735e9e8fd6092021-12-02T13:39:33ZQuantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy10.1038/s41467-021-22678-z2041-1723https://doaj.org/article/1e83db7f66c14a24885a735e9e8fd6092021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22678-zhttps://doaj.org/toc/2041-1723Quantification of intratumoral nanoparticles internalisation in vivo is crucial but challenging. Here, the authors develop a binary ratiometric nanoreporter that can quantify internalisation and predict nanotherapeutic responses based on intracellular nanoparticle exposure.Qingqing YinAnni PanBinlong ChenZenghui WangMingmei TangYue YanYaoqi WangHeming XiaWei ChenHongliang DuMeifang ChenChuanxun FuYanni WangXia YuanZhihao LuQiang ZhangYiguang WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qingqing Yin Anni Pan Binlong Chen Zenghui Wang Mingmei Tang Yue Yan Yaoqi Wang Heming Xia Wei Chen Hongliang Du Meifang Chen Chuanxun Fu Yanni Wang Xia Yuan Zhihao Lu Qiang Zhang Yiguang Wang Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy
description	Quantification of intratumoral nanoparticles internalisation in vivo is crucial but challenging. Here, the authors develop a binary ratiometric nanoreporter that can quantify internalisation and predict nanotherapeutic responses based on intracellular nanoparticle exposure.
format	article
author	Qingqing Yin Anni Pan Binlong Chen Zenghui Wang Mingmei Tang Yue Yan Yaoqi Wang Heming Xia Wei Chen Hongliang Du Meifang Chen Chuanxun Fu Yanni Wang Xia Yuan Zhihao Lu Qiang Zhang Yiguang Wang
author_facet	Qingqing Yin Anni Pan Binlong Chen Zenghui Wang Mingmei Tang Yue Yan Yaoqi Wang Heming Xia Wei Chen Hongliang Du Meifang Chen Chuanxun Fu Yanni Wang Xia Yuan Zhihao Lu Qiang Zhang Yiguang Wang
author_sort	Qingqing Yin
title	Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy
title_short	Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy
title_full	Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy
title_fullStr	Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy
title_full_unstemmed	Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy
title_sort	quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1e83db7f66c14a24885a735e9e8fd609
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_version_	1718392602622951424

Quantitative imaging of intracellular nanoparticle exposure enables prediction of nanotherapeutic efficacy

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