Role of blood urea nitrogen and serum albumin ratio in predicting severity of community acquired pneumonia (CAP)

Blood urea nitrogen and serum albumin levels are independent risk factors for poor clinical outcome in CAP. However, there is a paucity in the literature on the role of Blood urea nitrogen and albumin ratio(B/A) in CAP. This was a prospective observational study in which 112 admitted patients with...

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Autores principales: Mehul Agarwal, Madhur Joshi, Manohar Gupta, Neha Bharti, Amartya Chakraborti, Maldev Sonigra
Formato: article
Lenguaje:EN
Publicado: PAGEPress Publications 2021
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Acceso en línea:https://doaj.org/article/1e841497737b4bdcbff0819c2aebf23c
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spelling oai:doaj.org-article:1e841497737b4bdcbff0819c2aebf23c2021-12-04T07:48:21ZRole of blood urea nitrogen and serum albumin ratio in predicting severity of community acquired pneumonia (CAP)10.4081/monaldi.2021.20911122-06432532-5264https://doaj.org/article/1e841497737b4bdcbff0819c2aebf23c2021-12-01T00:00:00Zhttps://www.monaldi-archives.org/index.php/macd/article/view/2091https://doaj.org/toc/1122-0643https://doaj.org/toc/2532-5264 Blood urea nitrogen and serum albumin levels are independent risk factors for poor clinical outcome in CAP. However, there is a paucity in the literature on the role of Blood urea nitrogen and albumin ratio(B/A) in CAP. This was a prospective observational study in which 112 admitted patients with the diagnosis of CAP underwent routine blood examinations, ABG, procalcitonin and Chest X-ray. Univariate analysis among various risk factors, CURB-65 scores, blood parameters including B/A ratios and clinical outcomes were carried out followed by multiple logistic regression. Cox regression was done to look at B/A values and time to mortality. In the logistic regression, age, CURB -65 score, B/A ratio and procalcitonin came out to be independent risk factors for ICU admission and mortality. Odds ratio of B/A in predicting mortality and ICU admission came out to be 67.8 (49.2-95.4) and 11.2 (8.4-14), respectively. Cox regression showed B/A values were also found to have a statistically significant relationship with time to mortality (p=0.001). B/A ratio has the potential to become a veritable predictor of poor clinical outcomes in patients with CAP. Mehul AgarwalMadhur JoshiManohar GuptaNeha BhartiAmartya ChakrabortiMaldev SonigraPAGEPress PublicationsarticleB/A ratioCURB-65Community acquired pneumoniaMedicineRENMonaldi Archives for Chest Disease (2021)
institution DOAJ
collection DOAJ
language EN
topic B/A ratio
CURB-65
Community acquired pneumonia
Medicine
R
spellingShingle B/A ratio
CURB-65
Community acquired pneumonia
Medicine
R
Mehul Agarwal
Madhur Joshi
Manohar Gupta
Neha Bharti
Amartya Chakraborti
Maldev Sonigra
Role of blood urea nitrogen and serum albumin ratio in predicting severity of community acquired pneumonia (CAP)
description Blood urea nitrogen and serum albumin levels are independent risk factors for poor clinical outcome in CAP. However, there is a paucity in the literature on the role of Blood urea nitrogen and albumin ratio(B/A) in CAP. This was a prospective observational study in which 112 admitted patients with the diagnosis of CAP underwent routine blood examinations, ABG, procalcitonin and Chest X-ray. Univariate analysis among various risk factors, CURB-65 scores, blood parameters including B/A ratios and clinical outcomes were carried out followed by multiple logistic regression. Cox regression was done to look at B/A values and time to mortality. In the logistic regression, age, CURB -65 score, B/A ratio and procalcitonin came out to be independent risk factors for ICU admission and mortality. Odds ratio of B/A in predicting mortality and ICU admission came out to be 67.8 (49.2-95.4) and 11.2 (8.4-14), respectively. Cox regression showed B/A values were also found to have a statistically significant relationship with time to mortality (p=0.001). B/A ratio has the potential to become a veritable predictor of poor clinical outcomes in patients with CAP.
format article
author Mehul Agarwal
Madhur Joshi
Manohar Gupta
Neha Bharti
Amartya Chakraborti
Maldev Sonigra
author_facet Mehul Agarwal
Madhur Joshi
Manohar Gupta
Neha Bharti
Amartya Chakraborti
Maldev Sonigra
author_sort Mehul Agarwal
title Role of blood urea nitrogen and serum albumin ratio in predicting severity of community acquired pneumonia (CAP)
title_short Role of blood urea nitrogen and serum albumin ratio in predicting severity of community acquired pneumonia (CAP)
title_full Role of blood urea nitrogen and serum albumin ratio in predicting severity of community acquired pneumonia (CAP)
title_fullStr Role of blood urea nitrogen and serum albumin ratio in predicting severity of community acquired pneumonia (CAP)
title_full_unstemmed Role of blood urea nitrogen and serum albumin ratio in predicting severity of community acquired pneumonia (CAP)
title_sort role of blood urea nitrogen and serum albumin ratio in predicting severity of community acquired pneumonia (cap)
publisher PAGEPress Publications
publishDate 2021
url https://doaj.org/article/1e841497737b4bdcbff0819c2aebf23c
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AT madhurjoshi roleofbloodureanitrogenandserumalbuminratioinpredictingseverityofcommunityacquiredpneumoniacap
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