Luciferase Expression Allows Bioluminescence Imaging But Imposes Limitations on the Orthotopic Mouse (4T1) Model of Breast Cancer

Luciferase Expression Allows Bioluminescence Imaging But Imposes Limitations on the Orthotopic Mouse (4T1) Model of Breast Cancer

Abstract Implantation of reporter-labeled tumor cells in an immunocompetent host involves a risk of their immune elimination. We have studied this effect in a mouse model of breast cancer after the orthotopic implantation of mammary gland adenocarcinoma 4T1 cells genetically labelled with luciferase...

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Autores principales: V. P. Baklaushev, A. Kilpeläinen, S. Petkov, M. A. Abakumov, N. F. Grinenko, G. M. Yusubalieva, A. A. Latanova, I. L. Gubskiy, F. G. Zabozlaev, E. S. Starodubova, T. O. Abakumova, M. G. Isaguliants, V. P. Chekhonin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/1e8e0eebf76b4e3cbb74e7a11e8b17f1
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