Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods?
Cardiovascular intervention for myocardial revascularization dominates modern treatment of ischaemic heart disease (IHD). Current efficiency and safety of this method could never be achieved without the development of antiplatelet agents that provide indispensable protection for endovascular interve...
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Endocrinology Research Centre
2013
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oai:doaj.org-article:1ea0f7f3b1c54a869434ed4abbc4eb1e2021-11-14T09:00:18ZMechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods?2072-03512072-037810.14341/2072-0351-95https://doaj.org/article/1ea0f7f3b1c54a869434ed4abbc4eb1e2013-09-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/95https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Cardiovascular intervention for myocardial revascularization dominates modern treatment of ischaemic heart disease (IHD). Current efficiency and safety of this method could never be achieved without the development of antiplatelet agents that provide indispensable protection for endovascular interventions. However, antithrombotic therapy is generally less effective in diabetes mellitus (DM), affecting prognosis for transcutaneous intervention. This trend is probably due to alteration of cellular homeostasis during hyperglycemia and correlates with its severity and persistence. This paper addresses modern understanding of factors affecting thrombogenesis in patients with DM.Irina Ziyatovna BondarenkoIrina Alexandrovna ShirshinaEndocrinology Research Centrearticlediabetes mellitushaemostasisischaemic heart diseaseplatelet functionsNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 16, Iss 3, Pp 58-63 (2013) |
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diabetes mellitus haemostasis ischaemic heart disease platelet functions Nutritional diseases. Deficiency diseases RC620-627 |
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diabetes mellitus haemostasis ischaemic heart disease platelet functions Nutritional diseases. Deficiency diseases RC620-627 Irina Ziyatovna Bondarenko Irina Alexandrovna Shirshina Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
description |
Cardiovascular intervention for myocardial revascularization dominates modern treatment of ischaemic heart disease (IHD). Current efficiency and safety of this method could never be achieved without the development of antiplatelet agents that provide indispensable protection for endovascular interventions. However, antithrombotic therapy is generally less effective in diabetes mellitus (DM), affecting prognosis for transcutaneous intervention. This trend is probably due to alteration of cellular homeostasis during hyperglycemia and correlates with its severity and persistence. This paper addresses modern understanding of factors affecting thrombogenesis in patients with DM. |
format |
article |
author |
Irina Ziyatovna Bondarenko Irina Alexandrovna Shirshina |
author_facet |
Irina Ziyatovna Bondarenko Irina Alexandrovna Shirshina |
author_sort |
Irina Ziyatovna Bondarenko |
title |
Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
title_short |
Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
title_full |
Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
title_fullStr |
Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
title_full_unstemmed |
Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
title_sort |
mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
publisher |
Endocrinology Research Centre |
publishDate |
2013 |
url |
https://doaj.org/article/1ea0f7f3b1c54a869434ed4abbc4eb1e |
work_keys_str_mv |
AT irinaziyatovnabondarenko mechanismsofthrombogenesisassociatedwithdiabetesmellituswhatdefinestheprognosisofinvasivemyocardialrevascularizationmethods AT irinaalexandrovnashirshina mechanismsofthrombogenesisassociatedwithdiabetesmellituswhatdefinestheprognosisofinvasivemyocardialrevascularizationmethods |
_version_ |
1718429573741281280 |