Telomeric position effect--a third silencing mechanism in eukaryotes.

Eukaryotic chromosomes terminate in telomeres, complex nucleoprotein structures that are required for chromosome integrity that are implicated in cellular senescence and cancer. The chromatin at the telomere is unique with characteristics of both heterochromatin and euchromatin. The end of the chrom...

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Autores principales: J Greg Doheny, Randy Mottus, Thomas A Grigliatti
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/1eaa39f529ca494baf0b6c382c1fe954
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