Near-infrared reflectance bull’s eye maculopathy as an early indication of hydroxychloroquine toxicity

Near-infrared reflectance bull’s eye maculopathy as an early indication of hydroxychloroquine toxicity

Keye L Wong,1 Scott E Pautler,2 David J Browning31Retina Associates of Sarasota, Sarasota, FL, USA; 2Retina Vitreous Associates of Florida, Tampa, FL, USA; 3Charlotte Eye Ear Nose and Throat Associates, Charlotte, NC, USAImportance: In some patients, hydroxychloroquine ocular toxicity may progress...

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Autores principales: Wong KL, Pautler SE, Browning DJ
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2015
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Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/1eb4ba871fdd4c27a3c381a3f711bfda
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spelling oai:doaj.org-article:1eb4ba871fdd4c27a3c381a3f711bfda2021-12-02T01:12:45ZNear-infrared reflectance bull’s eye maculopathy as an early indication of hydroxychloroquine toxicity1177-5483https://doaj.org/article/1eb4ba871fdd4c27a3c381a3f711bfda2015-03-01T00:00:00Zhttp://www.dovepress.com/near-infrared-reflectance-bullrsquos-eye-maculopathy-as-an-early-indic-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483 Keye L Wong,1 Scott E Pautler,2 David J Browning31Retina Associates of Sarasota, Sarasota, FL, USA; 2Retina Vitreous Associates of Florida, Tampa, FL, USA; 3Charlotte Eye Ear Nose and Throat Associates, Charlotte, NC, USAImportance: In some patients, hydroxychloroquine ocular toxicity may progress even following cessation of therapy. Any leverage the clinician may use to allow earlier detection may avert significant vision loss.Observation: We report three cases suggesting that bull’s eye maculopathy seen on near-infrared reflectance with a confocal scanning laser ophthalmoscope could be an early, objective manifestation of hydroxychloroquine ocular toxicity, and with progression of the disease this near-infrared “bull’s eye” change may disappear.Conclusion and relevance: Alerting clinicians to this observation may allow a larger case series to corroborate the hypothesis that bull’s eye maculopathy detected by near-infrared reflectance may represent an early sign of hydroxychloroquine toxicity.Keywords: confocal, scanning laser ophthalmoscope, multifocal ERGWong KLPautler SEBrowning DJDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 521-525 (2015)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Wong KL
Pautler SE
Browning DJ
Near-infrared reflectance bull’s eye maculopathy as an early indication of hydroxychloroquine toxicity
description Keye L Wong,1 Scott E Pautler,2 David J Browning31Retina Associates of Sarasota, Sarasota, FL, USA; 2Retina Vitreous Associates of Florida, Tampa, FL, USA; 3Charlotte Eye Ear Nose and Throat Associates, Charlotte, NC, USAImportance: In some patients, hydroxychloroquine ocular toxicity may progress even following cessation of therapy. Any leverage the clinician may use to allow earlier detection may avert significant vision loss.Observation: We report three cases suggesting that bull’s eye maculopathy seen on near-infrared reflectance with a confocal scanning laser ophthalmoscope could be an early, objective manifestation of hydroxychloroquine ocular toxicity, and with progression of the disease this near-infrared “bull’s eye” change may disappear.Conclusion and relevance: Alerting clinicians to this observation may allow a larger case series to corroborate the hypothesis that bull’s eye maculopathy detected by near-infrared reflectance may represent an early sign of hydroxychloroquine toxicity.Keywords: confocal, scanning laser ophthalmoscope, multifocal ERG
format article
author Wong KL
Pautler SE
Browning DJ
author_facet Wong KL
Pautler SE
Browning DJ
author_sort Wong KL
title Near-infrared reflectance bull’s eye maculopathy as an early indication of hydroxychloroquine toxicity
title_short Near-infrared reflectance bull’s eye maculopathy as an early indication of hydroxychloroquine toxicity
title_full Near-infrared reflectance bull’s eye maculopathy as an early indication of hydroxychloroquine toxicity
title_fullStr Near-infrared reflectance bull’s eye maculopathy as an early indication of hydroxychloroquine toxicity
title_full_unstemmed Near-infrared reflectance bull’s eye maculopathy as an early indication of hydroxychloroquine toxicity
title_sort near-infrared reflectance bull’s eye maculopathy as an early indication of hydroxychloroquine toxicity
publisher Dove Medical Press
publishDate 2015
url https://doaj.org/article/1eb4ba871fdd4c27a3c381a3f711bfda
work_keys_str_mv AT wongkl nearinfraredreflectancebullrsquoseyemaculopathyasanearlyindicationofhydroxychloroquinetoxicity
AT pautlerse nearinfraredreflectancebullrsquoseyemaculopathyasanearlyindicationofhydroxychloroquinetoxicity
AT browningdj nearinfraredreflectancebullrsquoseyemaculopathyasanearlyindicationofhydroxychloroquinetoxicity
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