Giant left anterior descending artery aneurysm in a patient with active systemic lupus erythematosus: a case report

Abstract Background Although not common, coronary artery aneurysms (CAAs) can develop to over 8 mm in diameter to become giant CAAs. In the context of systemic lupus erythematosus (SLE), autoantibody- and immune complex-mediated atherosclerosis is believed to be the most prevalent cause of aneurysm....

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Autores principales:	Zipeng Yao, Yanhong Long, Zheng Zong, Lin Wang
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Systemic lupus erythematosus Coronary artery aneurysm Coronary angiography Surgery RD1-811 Anesthesiology RD78.3-87.3
Acceso en línea:	https://doaj.org/article/1eb98ea5bc5d43a49de90e00359a5479
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spelling	oai:doaj.org-article:1eb98ea5bc5d43a49de90e00359a54792021-11-28T12:30:59ZGiant left anterior descending artery aneurysm in a patient with active systemic lupus erythematosus: a case report10.1186/s13019-021-01725-21749-8090https://doaj.org/article/1eb98ea5bc5d43a49de90e00359a54792021-11-01T00:00:00Zhttps://doi.org/10.1186/s13019-021-01725-2https://doaj.org/toc/1749-8090Abstract Background Although not common, coronary artery aneurysms (CAAs) can develop to over 8 mm in diameter to become giant CAAs. In the context of systemic lupus erythematosus (SLE), autoantibody- and immune complex-mediated atherosclerosis is believed to be the most prevalent cause of aneurysm. Case presentation We report the case of a 53-year-old female SLE patient who presented to our hospital with radiating chest pain. Coronary angiography revealed a giant aneurysm in the middle segment of the left anterior descending artery (LAD) and distal subtotal occlusion in the left circumflex artery (LCX). Laboratory testing also identified risk factors such as an abnormal pulmonary enzyme profile, dyslipidemia, and nephritis parameters.To prevent thromboembolism, anticoagulation and antiplatelet therapy were administered. In addition, one stent was implanted at the distal end of the LCX and repeated coronary angiography verified restoration of TIMI grade III flow.The patient was discharged with resolved chest pain. During 6 months of follow-up, the patient is in good health. Conclusions Our case study, together with 16 recent comparable reports, emphasizes the need for coronary aneurysm screening in SLE patients. It is necessary that thromboembolism, anticoagulation and antiplatelet therapy were administered for CAA.Zipeng YaoYanhong LongZheng ZongLin WangBMCarticleSystemic lupus erythematosusCoronary artery aneurysmCoronary angiographySurgeryRD1-811AnesthesiologyRD78.3-87.3ENJournal of Cardiothoracic Surgery, Vol 16, Iss 1, Pp 1-5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Systemic lupus erythematosus Coronary artery aneurysm Coronary angiography Surgery RD1-811 Anesthesiology RD78.3-87.3
spellingShingle	Systemic lupus erythematosus Coronary artery aneurysm Coronary angiography Surgery RD1-811 Anesthesiology RD78.3-87.3 Zipeng Yao Yanhong Long Zheng Zong Lin Wang Giant left anterior descending artery aneurysm in a patient with active systemic lupus erythematosus: a case report
description	Abstract Background Although not common, coronary artery aneurysms (CAAs) can develop to over 8 mm in diameter to become giant CAAs. In the context of systemic lupus erythematosus (SLE), autoantibody- and immune complex-mediated atherosclerosis is believed to be the most prevalent cause of aneurysm. Case presentation We report the case of a 53-year-old female SLE patient who presented to our hospital with radiating chest pain. Coronary angiography revealed a giant aneurysm in the middle segment of the left anterior descending artery (LAD) and distal subtotal occlusion in the left circumflex artery (LCX). Laboratory testing also identified risk factors such as an abnormal pulmonary enzyme profile, dyslipidemia, and nephritis parameters.To prevent thromboembolism, anticoagulation and antiplatelet therapy were administered. In addition, one stent was implanted at the distal end of the LCX and repeated coronary angiography verified restoration of TIMI grade III flow.The patient was discharged with resolved chest pain. During 6 months of follow-up, the patient is in good health. Conclusions Our case study, together with 16 recent comparable reports, emphasizes the need for coronary aneurysm screening in SLE patients. It is necessary that thromboembolism, anticoagulation and antiplatelet therapy were administered for CAA.
format	article
author	Zipeng Yao Yanhong Long Zheng Zong Lin Wang
author_facet	Zipeng Yao Yanhong Long Zheng Zong Lin Wang
author_sort	Zipeng Yao
title	Giant left anterior descending artery aneurysm in a patient with active systemic lupus erythematosus: a case report
title_short	Giant left anterior descending artery aneurysm in a patient with active systemic lupus erythematosus: a case report
title_full	Giant left anterior descending artery aneurysm in a patient with active systemic lupus erythematosus: a case report
title_fullStr	Giant left anterior descending artery aneurysm in a patient with active systemic lupus erythematosus: a case report
title_full_unstemmed	Giant left anterior descending artery aneurysm in a patient with active systemic lupus erythematosus: a case report
title_sort	giant left anterior descending artery aneurysm in a patient with active systemic lupus erythematosus: a case report
publisher	BMC
publishDate	2021
url	https://doaj.org/article/1eb98ea5bc5d43a49de90e00359a5479
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Giant left anterior descending artery aneurysm in a patient with active systemic lupus erythematosus: a case report

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