Chloroquine Potentiates the Anticancer Effect of Pterostilbene on Pancreatic Cancer by Inhibiting Autophagy and Downregulating the RAGE/STAT3 Pathway

The treatment of pancreatic ductal adenocarcinoma (PDAC) remains a huge challenge, because pro-survival signaling pathways—such as the receptor for advanced glycation end products (RAGE)/signal transducer and activator of transcription 3 (STAT3) pathway—are overexpressed in PDAC cells. Moreover, PDA...

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Bibliographic Details
Main Authors: Rong-Jane Chen, Yi-Jhen Lyu, Yu-Ying Chen, Yen-Chien Lee, Min-Hsiung Pan, Yuan-Soon Ho, Ying-Jan Wang
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/1ecc510839574922bf82ba1ac4f3fdfc
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