Mining predicted essential genes of Brugia malayi for nematode drug targets.

Mining predicted essential genes of Brugia malayi for nematode drug targets.

We report results from the first genome-wide application of a rational drug target selection methodology to a metazoan pathogen genome, the completed draft sequence of Brugia malayi, a parasitic nematode responsible for human lymphatic filariasis. More than 1.5 billion people worldwide are at risk o...

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Autores principales: Sanjay Kumar, Kshitiz Chaudhary, Jeremy M Foster, Jacopo F Novelli, Yinhua Zhang, Shiliang Wang, David Spiro, Elodie Ghedin, Clotilde K S Carlow
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2007
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1ecfd8f6c9a14b828ce7f8c686abce52
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