Divergent synthesis and identification of the cellular targets of deoxyelephantopins

Deoxyelephantopin is a naturally occurring sesquiterpene lactone with known anticancer properties. Here, the authors synthesize deoxyelephantopins and a range of analogues including alkyne-tagged probes, using them to identify its cellular targets.

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Autores principales:	Roman Lagoutte, Christelle Serba, Daniel Abegg, Dominic G. Hoch, Alexander Adibekian, Nicolas Winssinger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1ed6d7b632384db6874986b87650499b
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spelling	oai:doaj.org-article:1ed6d7b632384db6874986b87650499b2021-12-02T14:40:16ZDivergent synthesis and identification of the cellular targets of deoxyelephantopins10.1038/ncomms124702041-1723https://doaj.org/article/1ed6d7b632384db6874986b87650499b2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12470https://doaj.org/toc/2041-1723Deoxyelephantopin is a naturally occurring sesquiterpene lactone with known anticancer properties. Here, the authors synthesize deoxyelephantopins and a range of analogues including alkyne-tagged probes, using them to identify its cellular targets.Roman LagoutteChristelle SerbaDaniel AbeggDominic G. HochAlexander AdibekianNicolas WinssingerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Roman Lagoutte Christelle Serba Daniel Abegg Dominic G. Hoch Alexander Adibekian Nicolas Winssinger Divergent synthesis and identification of the cellular targets of deoxyelephantopins
description	Deoxyelephantopin is a naturally occurring sesquiterpene lactone with known anticancer properties. Here, the authors synthesize deoxyelephantopins and a range of analogues including alkyne-tagged probes, using them to identify its cellular targets.
format	article
author	Roman Lagoutte Christelle Serba Daniel Abegg Dominic G. Hoch Alexander Adibekian Nicolas Winssinger
author_facet	Roman Lagoutte Christelle Serba Daniel Abegg Dominic G. Hoch Alexander Adibekian Nicolas Winssinger
author_sort	Roman Lagoutte
title	Divergent synthesis and identification of the cellular targets of deoxyelephantopins
title_short	Divergent synthesis and identification of the cellular targets of deoxyelephantopins
title_full	Divergent synthesis and identification of the cellular targets of deoxyelephantopins
title_fullStr	Divergent synthesis and identification of the cellular targets of deoxyelephantopins
title_full_unstemmed	Divergent synthesis and identification of the cellular targets of deoxyelephantopins
title_sort	divergent synthesis and identification of the cellular targets of deoxyelephantopins
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/1ed6d7b632384db6874986b87650499b
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Divergent synthesis and identification of the cellular targets of deoxyelephantopins

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