Divergent synthesis and identification of the cellular targets of deoxyelephantopins

Divergent synthesis and identification of the cellular targets of deoxyelephantopins

Deoxyelephantopin is a naturally occurring sesquiterpene lactone with known anticancer properties. Here, the authors synthesize deoxyelephantopins and a range of analogues including alkyne-tagged probes, using them to identify its cellular targets.

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Detalles Bibliográficos
Autores principales: Roman Lagoutte, Christelle Serba, Daniel Abegg, Dominic G. Hoch, Alexander Adibekian, Nicolas Winssinger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/1ed6d7b632384db6874986b87650499b
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