Genomic RNA folding mediates assembly of human parechovirus

Genomic RNA folding mediates assembly of human parechovirus

The mechanism underlying packaging of genomic RNA into viral particles is not well understood for human parechoviruses. Here the authors identify short RNA motifs in the parechovirus genome that bind capsid proteins, providing approximately 60 specific interactions for virion assembly.

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Autores principales: Shabih Shakeel, Eric C. Dykeman, Simon J. White, Ari Ora, Joseph J.B. Cockburn, Sarah J. Butcher, Peter G. Stockley, Reidun Twarock
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/1edc545ea86c44ca9bf0cec5084edbad
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