Selective suppression of antisense transcription by Set2-mediated H3K36 methylation

Maintenance of chromatin structure in coding regions is partially dependent on transcription, with histone methyltransferase Set2 playing a role in this process. Here, the authors provide evidence that Set2 regulates repression of a specific set of antisense RNAs embedded within the coding genes.

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Detalles Bibliográficos
Autores principales: Swaminathan Venkatesh, Hua Li, Madelaine M. Gogol, Jerry L. Workman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/1ef059dc47f940508d6d5a9b3cc1e47b
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Sumario:Maintenance of chromatin structure in coding regions is partially dependent on transcription, with histone methyltransferase Set2 playing a role in this process. Here, the authors provide evidence that Set2 regulates repression of a specific set of antisense RNAs embedded within the coding genes.