Selective suppression of antisense transcription by Set2-mediated H3K36 methylation

Maintenance of chromatin structure in coding regions is partially dependent on transcription, with histone methyltransferase Set2 playing a role in this process. Here, the authors provide evidence that Set2 regulates repression of a specific set of antisense RNAs embedded within the coding genes.

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Autores principales: Swaminathan Venkatesh, Hua Li, Madelaine M. Gogol, Jerry L. Workman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/1ef059dc47f940508d6d5a9b3cc1e47b
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spelling oai:doaj.org-article:1ef059dc47f940508d6d5a9b3cc1e47b2021-12-02T16:57:05ZSelective suppression of antisense transcription by Set2-mediated H3K36 methylation10.1038/ncomms136102041-1723https://doaj.org/article/1ef059dc47f940508d6d5a9b3cc1e47b2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13610https://doaj.org/toc/2041-1723Maintenance of chromatin structure in coding regions is partially dependent on transcription, with histone methyltransferase Set2 playing a role in this process. Here, the authors provide evidence that Set2 regulates repression of a specific set of antisense RNAs embedded within the coding genes.Swaminathan VenkateshHua LiMadelaine M. GogolJerry L. WorkmanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Swaminathan Venkatesh
Hua Li
Madelaine M. Gogol
Jerry L. Workman
Selective suppression of antisense transcription by Set2-mediated H3K36 methylation
description Maintenance of chromatin structure in coding regions is partially dependent on transcription, with histone methyltransferase Set2 playing a role in this process. Here, the authors provide evidence that Set2 regulates repression of a specific set of antisense RNAs embedded within the coding genes.
format article
author Swaminathan Venkatesh
Hua Li
Madelaine M. Gogol
Jerry L. Workman
author_facet Swaminathan Venkatesh
Hua Li
Madelaine M. Gogol
Jerry L. Workman
author_sort Swaminathan Venkatesh
title Selective suppression of antisense transcription by Set2-mediated H3K36 methylation
title_short Selective suppression of antisense transcription by Set2-mediated H3K36 methylation
title_full Selective suppression of antisense transcription by Set2-mediated H3K36 methylation
title_fullStr Selective suppression of antisense transcription by Set2-mediated H3K36 methylation
title_full_unstemmed Selective suppression of antisense transcription by Set2-mediated H3K36 methylation
title_sort selective suppression of antisense transcription by set2-mediated h3k36 methylation
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/1ef059dc47f940508d6d5a9b3cc1e47b
work_keys_str_mv AT swaminathanvenkatesh selectivesuppressionofantisensetranscriptionbyset2mediatedh3k36methylation
AT huali selectivesuppressionofantisensetranscriptionbyset2mediatedh3k36methylation
AT madelainemgogol selectivesuppressionofantisensetranscriptionbyset2mediatedh3k36methylation
AT jerrylworkman selectivesuppressionofantisensetranscriptionbyset2mediatedh3k36methylation
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