Development of Heptylmannoside-Based Glycoconjugate Antiadhesive Compounds against Adherent-Invasive <named-content content-type="genus-species">Escherichia coli</named-content> Bacteria Associated with Crohn's Disease
ABSTRACT The ileal lesions of Crohn's disease (CD) patients are colonized by adherent-invasive Escherichia coli (AIEC) bacteria. These bacteria adhere to mannose residues expressed by CEACAM6 on host cells in a type 1 pilus-dependent manner. In this study, we investigated different antagonists...
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Autores principales: | , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://doaj.org/article/1ef07e44bddd4567876566ae20c1d360 |
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