Emerging hematological targets and therapy for cardiovascular disease: From bench to bedside

Ana Villegas, Fernando A Gonzalez, Leopoldo Llorente, Santiago RedondoService of Hematology and Hemotherapy, Hospital Clinico Universitario San Carlos, Madrid, SpainAbstract: Atherosclerotic cardiovascular disease is the leading cause of death and a major part of its pathophysiology remains obscure....

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Autores principales:	Ana Villegas, Fernando A Gonzalez, Leopoldo Llorente, Santiago Redondo
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/1ef7c8f9ebc54c64bed1ad8d588800f8
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id	oai:doaj.org-article:1ef7c8f9ebc54c64bed1ad8d588800f8
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spelling	oai:doaj.org-article:1ef7c8f9ebc54c64bed1ad8d588800f82021-12-02T01:26:45ZEmerging hematological targets and therapy for cardiovascular disease: From bench to bedside1177-54751177-5491https://doaj.org/article/1ef7c8f9ebc54c64bed1ad8d588800f82008-09-01T00:00:00Zhttp://www.dovepress.com/emerging-hematological-targets-and-therapy-for-cardiovascular-disease--a2290https://doaj.org/toc/1177-5475https://doaj.org/toc/1177-5491Ana Villegas, Fernando A Gonzalez, Leopoldo Llorente, Santiago RedondoService of Hematology and Hemotherapy, Hospital Clinico Universitario San Carlos, Madrid, SpainAbstract: Atherosclerotic cardiovascular disease is the leading cause of death and a major part of its pathophysiology remains obscure. Some hematological targets have been related to the development and clinical outcome of this disease, especially soluble cytokines, leukocytes, red blood cells, hemostatic factors and platelets, and bone-marrow vascular progenitors. These emerging factors may be modulated by current antiatherosclerotic pharmacotherapy, target-designed novel drugs or progenitor cell therapy. The aim of current review article is to comprehensively review the role of these antiatherosclerotic targets and therapy.Keywords: atherosclerosis, blood, progenitor cells, cytokines, therapy Ana VillegasFernando A GonzalezLeopoldo LlorenteSantiago RedondoDove Medical PressarticleMedicine (General)R5-920ENBiologics: Targets & Therapy, Vol 2008, Iss Issue 3, Pp 397-407 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Ana Villegas Fernando A Gonzalez Leopoldo Llorente Santiago Redondo Emerging hematological targets and therapy for cardiovascular disease: From bench to bedside
description	Ana Villegas, Fernando A Gonzalez, Leopoldo Llorente, Santiago RedondoService of Hematology and Hemotherapy, Hospital Clinico Universitario San Carlos, Madrid, SpainAbstract: Atherosclerotic cardiovascular disease is the leading cause of death and a major part of its pathophysiology remains obscure. Some hematological targets have been related to the development and clinical outcome of this disease, especially soluble cytokines, leukocytes, red blood cells, hemostatic factors and platelets, and bone-marrow vascular progenitors. These emerging factors may be modulated by current antiatherosclerotic pharmacotherapy, target-designed novel drugs or progenitor cell therapy. The aim of current review article is to comprehensively review the role of these antiatherosclerotic targets and therapy.Keywords: atherosclerosis, blood, progenitor cells, cytokines, therapy
format	article
author	Ana Villegas Fernando A Gonzalez Leopoldo Llorente Santiago Redondo
author_facet	Ana Villegas Fernando A Gonzalez Leopoldo Llorente Santiago Redondo
author_sort	Ana Villegas
title	Emerging hematological targets and therapy for cardiovascular disease: From bench to bedside
title_short	Emerging hematological targets and therapy for cardiovascular disease: From bench to bedside
title_full	Emerging hematological targets and therapy for cardiovascular disease: From bench to bedside
title_fullStr	Emerging hematological targets and therapy for cardiovascular disease: From bench to bedside
title_full_unstemmed	Emerging hematological targets and therapy for cardiovascular disease: From bench to bedside
title_sort	emerging hematological targets and therapy for cardiovascular disease: from bench to bedside
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/1ef7c8f9ebc54c64bed1ad8d588800f8
work_keys_str_mv	AT anavillegas emerginghematologicaltargetsandtherapyforcardiovasculardiseasefrombenchtobedside AT fernandoagonzalez emerginghematologicaltargetsandtherapyforcardiovasculardiseasefrombenchtobedside AT leopoldollorente emerginghematologicaltargetsandtherapyforcardiovasculardiseasefrombenchtobedside AT santiagoredondo emerginghematologicaltargetsandtherapyforcardiovasculardiseasefrombenchtobedside
_version_	1718403059586957312

Emerging hematological targets and therapy for cardiovascular disease: From bench to bedside

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