Association between multiple sclerosis and dietary patterns based on the traditional concept of food nature: a case-control study in Iran

Abstract Introduction It remains a matter of debate whether traditional concepts regarding the nature of food affect the development and progression of multiple sclerosis (MS).To date, there are limited studies that have investigated the association between MS and dietary patterns based on the categ...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mohammad Hossein Sharifi, Parisa Keshani, Alireza Salehi, Amir Mohammad Jaladat, Zahra Mirzaei, Alireza Nikseresht
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Multiple sclerosis Dietary pattern Food nature concept Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/1f010bc7f5894d3190a65ce9f98c2a52
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1f010bc7f5894d3190a65ce9f98c2a52
record_format	dspace
spelling	oai:doaj.org-article:1f010bc7f5894d3190a65ce9f98c2a522021-11-21T12:09:40ZAssociation between multiple sclerosis and dietary patterns based on the traditional concept of food nature: a case-control study in Iran10.1186/s12883-021-02483-31471-2377https://doaj.org/article/1f010bc7f5894d3190a65ce9f98c2a522021-11-01T00:00:00Zhttps://doi.org/10.1186/s12883-021-02483-3https://doaj.org/toc/1471-2377Abstract Introduction It remains a matter of debate whether traditional concepts regarding the nature of food affect the development and progression of multiple sclerosis (MS).To date, there are limited studies that have investigated the association between MS and dietary patterns based on the categories of food nature (hot, cold, or balanced) defined in traditional medicine. Method This case-control study was conducted from October 2019 to February 2020. In total, 60 patients diagnosed with MS within the preceding 6 months and referred to our neurology outpatient clinic were included in our case group. The control group included 180 patients who were referred to the same center for general or orthopedic surgery. Dietary intake was assessed in both groups through a reliable and valid semi-quantitative food frequency questionnaire. Data were assessed using principal component analysis. Results The mean age of the participants was 44.9 ± 17.33 years. The analysis showed that four food patterns were distinguished (eigenvalue > 1), namely “additives and cold-natured foods”, “hot and balanced foods and nuts”, “dairy and legumes”, and “hot and balanced starches”. These food patterns explained 57.8% of the total variance. After adjusting all confounding factors, individuals in the highest quartile and medium quartile of “additives and cold-natured foods” had an elevated MS risk compared with the lowest quartile (OR = 7.21, 95%CI = 2.01–12.38 and OR = 3.37, 95%CI = 1.02–11.35, respectively). Furthermore, individuals in the highest quartile of the “hot and balanced foods and nuts” group were protected against MS compared with its lowest quartile (OR = 0.28, 95%CI = 0.08–0.90). Moreover, a protective effect against MS was seen in the highest quartile of the “hot and balanced starches” group relative to its lowest quartile (OR = 0.34, 95%CI = 0.12–0.98). No significant association was found between “dairy and legumes” and the risk of MS. Conclusion This study revealed that dietary patterns based on the traditional concept of food nature might be associated with the risk of developing MS. This represents the first work in this area, so further research is recommended.Mohammad Hossein SharifiParisa KeshaniAlireza SalehiAmir Mohammad JaladatZahra MirzaeiAlireza NiksereshtBMCarticleMultiple sclerosisDietary patternFood nature conceptNeurology. Diseases of the nervous systemRC346-429ENBMC Neurology, Vol 21, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Multiple sclerosis Dietary pattern Food nature concept Neurology. Diseases of the nervous system RC346-429
spellingShingle	Multiple sclerosis Dietary pattern Food nature concept Neurology. Diseases of the nervous system RC346-429 Mohammad Hossein Sharifi Parisa Keshani Alireza Salehi Amir Mohammad Jaladat Zahra Mirzaei Alireza Nikseresht Association between multiple sclerosis and dietary patterns based on the traditional concept of food nature: a case-control study in Iran
description	Abstract Introduction It remains a matter of debate whether traditional concepts regarding the nature of food affect the development and progression of multiple sclerosis (MS).To date, there are limited studies that have investigated the association between MS and dietary patterns based on the categories of food nature (hot, cold, or balanced) defined in traditional medicine. Method This case-control study was conducted from October 2019 to February 2020. In total, 60 patients diagnosed with MS within the preceding 6 months and referred to our neurology outpatient clinic were included in our case group. The control group included 180 patients who were referred to the same center for general or orthopedic surgery. Dietary intake was assessed in both groups through a reliable and valid semi-quantitative food frequency questionnaire. Data were assessed using principal component analysis. Results The mean age of the participants was 44.9 ± 17.33 years. The analysis showed that four food patterns were distinguished (eigenvalue > 1), namely “additives and cold-natured foods”, “hot and balanced foods and nuts”, “dairy and legumes”, and “hot and balanced starches”. These food patterns explained 57.8% of the total variance. After adjusting all confounding factors, individuals in the highest quartile and medium quartile of “additives and cold-natured foods” had an elevated MS risk compared with the lowest quartile (OR = 7.21, 95%CI = 2.01–12.38 and OR = 3.37, 95%CI = 1.02–11.35, respectively). Furthermore, individuals in the highest quartile of the “hot and balanced foods and nuts” group were protected against MS compared with its lowest quartile (OR = 0.28, 95%CI = 0.08–0.90). Moreover, a protective effect against MS was seen in the highest quartile of the “hot and balanced starches” group relative to its lowest quartile (OR = 0.34, 95%CI = 0.12–0.98). No significant association was found between “dairy and legumes” and the risk of MS. Conclusion This study revealed that dietary patterns based on the traditional concept of food nature might be associated with the risk of developing MS. This represents the first work in this area, so further research is recommended.
format	article
author	Mohammad Hossein Sharifi Parisa Keshani Alireza Salehi Amir Mohammad Jaladat Zahra Mirzaei Alireza Nikseresht
author_facet	Mohammad Hossein Sharifi Parisa Keshani Alireza Salehi Amir Mohammad Jaladat Zahra Mirzaei Alireza Nikseresht
author_sort	Mohammad Hossein Sharifi
title	Association between multiple sclerosis and dietary patterns based on the traditional concept of food nature: a case-control study in Iran
title_short	Association between multiple sclerosis and dietary patterns based on the traditional concept of food nature: a case-control study in Iran
title_full	Association between multiple sclerosis and dietary patterns based on the traditional concept of food nature: a case-control study in Iran
title_fullStr	Association between multiple sclerosis and dietary patterns based on the traditional concept of food nature: a case-control study in Iran
title_full_unstemmed	Association between multiple sclerosis and dietary patterns based on the traditional concept of food nature: a case-control study in Iran
title_sort	association between multiple sclerosis and dietary patterns based on the traditional concept of food nature: a case-control study in iran
publisher	BMC
publishDate	2021
url	https://doaj.org/article/1f010bc7f5894d3190a65ce9f98c2a52
work_keys_str_mv	AT mohammadhosseinsharifi associationbetweenmultiplesclerosisanddietarypatternsbasedonthetraditionalconceptoffoodnatureacasecontrolstudyiniran AT parisakeshani associationbetweenmultiplesclerosisanddietarypatternsbasedonthetraditionalconceptoffoodnatureacasecontrolstudyiniran AT alirezasalehi associationbetweenmultiplesclerosisanddietarypatternsbasedonthetraditionalconceptoffoodnatureacasecontrolstudyiniran AT amirmohammadjaladat associationbetweenmultiplesclerosisanddietarypatternsbasedonthetraditionalconceptoffoodnatureacasecontrolstudyiniran AT zahramirzaei associationbetweenmultiplesclerosisanddietarypatternsbasedonthetraditionalconceptoffoodnatureacasecontrolstudyiniran AT alirezanikseresht associationbetweenmultiplesclerosisanddietarypatternsbasedonthetraditionalconceptoffoodnatureacasecontrolstudyiniran
_version_	1718419172473438208

Association between multiple sclerosis and dietary patterns based on the traditional concept of food nature: a case-control study in Iran

Ejemplares similares