A DNA origami-based aptamer nanoarray for potent and reversible anticoagulation in hemodialysis

Safe haemodialysis is essential for patients with acute kidney injury and renal failure. Here the authors present a DNA origami-based approach with high affinity and specificity to thrombin, inhibiting coagulation.

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Detalles Bibliográficos
Autores principales: Shuai Zhao, Run Tian, Jun Wu, Shaoli Liu, Yuanning Wang, Meng Wen, Yingxu Shang, Qing Liu, Yan Li, Ying Guo, Zhaoran Wang, Ting Wang, Yujing Zhao, Huiru Zhao, Hui Cao, Yu Su, Jiashu Sun, Qiao Jiang, Baoquan Ding
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1f01550336d84082a3d6c635dadf7846
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Descripción
Sumario:Safe haemodialysis is essential for patients with acute kidney injury and renal failure. Here the authors present a DNA origami-based approach with high affinity and specificity to thrombin, inhibiting coagulation.